Molecular insight into arrhythmogenic cardiomyopathy caused by DSG2 mutations

Molecular insight into arrhythmogenic cardiomyopathy caused by DSG2 mutations

Mutant desmoglein 2 (DSG2) is the second most common pathogenic gene in arrhythmogenic cardiomyopathy (ACM), accounting for approximately 10% of ACM cases. In addition to common clinical and pathological features, ACM caused by mutant DSG2 has specific characteristics, manifesting as left ventricle...

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Bibliographic Details
Main Authors: Baowei Zhang, Yizhang Wu, Xingbo Yang, Yaozu Xiang, Bing Yang
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Arrhythmogenic cardiomyopathy
Desmoglein 2
Desmosome dysfunction
Inflammation
Cardiac fibrosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223012465

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