Age features of the thymocite RNA response in the thymus structural and functional areas to blood circulation disorders in the pool of carotic arteries in rats

Introduction. Ischemic-reperfusion injuries of the brain are accompanied by immunological disorders, which in their turn can extend post-ischemic changes in the brain. The studies of structural and functional changes in the thymus cells caused byischemia-reperfusion of the brain can supplement the...

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Main Authors: S. Tkachuk, O. Tkachuk, O. Denysenko, O. Yasinska, O. Garvasiuk
Format: Article
Language:English
Published: Kazimierz Wielki University 2023-08-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:https://apcz.umk.pl/JEHS/article/view/46639
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author S. Tkachuk
O. Tkachuk
O. Denysenko
O. Yasinska
O. Garvasiuk
author_facet S. Tkachuk
O. Tkachuk
O. Denysenko
O. Yasinska
O. Garvasiuk
author_sort S. Tkachuk
collection DOAJ
description Introduction. Ischemic-reperfusion injuries of the brain are accompanied by immunological disorders, which in their turn can extend post-ischemic changes in the brain. The studies of structural and functional changes in the thymus cells caused byischemia-reperfusion of the brain can supplement the existing understanding of the mechanism of the above interaction. The aim of the study. To investigate the reaction of thymocyte RNA in the structural and functional areas of the thymus gland to blood circulation disturbances in the carotid artery pool. Results. In rats of both age groups, cerebral ischemia-reperfusion reduces the content of RNA in the thymus cells in all the structural and functional areas of the thymus except the deep cortical one in one-month rats and the sub-capsular one in three-month rats.  Conclusions. Acute circulatory disorders in the pool of the carotid arteries result in certain changes in RNA content in all the structural and functional areas of the thymus with age-related and structural features available.
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spelling doaj.art-91220f09afe14b98b415fd43bfc8030f2023-10-31T11:50:16ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062023-08-0147110.12775/JEHS.2023.47.01.012Age features of the thymocite RNA response in the thymus structural and functional areas to blood circulation disorders in the pool of carotic arteries in ratsS. Tkachuk0O. Tkachuk1O. Denysenko2O. Yasinska3O. Garvasiuk4Bukovinian State Medical UniversityBukovinian State Medical UniversityBukovinian State Medical UniversityBukovinian State Medical UniversityBukovinian State Medical University Introduction. Ischemic-reperfusion injuries of the brain are accompanied by immunological disorders, which in their turn can extend post-ischemic changes in the brain. The studies of structural and functional changes in the thymus cells caused byischemia-reperfusion of the brain can supplement the existing understanding of the mechanism of the above interaction. The aim of the study. To investigate the reaction of thymocyte RNA in the structural and functional areas of the thymus gland to blood circulation disturbances in the carotid artery pool. Results. In rats of both age groups, cerebral ischemia-reperfusion reduces the content of RNA in the thymus cells in all the structural and functional areas of the thymus except the deep cortical one in one-month rats and the sub-capsular one in three-month rats.  Conclusions. Acute circulatory disorders in the pool of the carotid arteries result in certain changes in RNA content in all the structural and functional areas of the thymus with age-related and structural features available. https://apcz.umk.pl/JEHS/article/view/46639incomplete global cerebral ischemia-reperfusioncells of the thymus lymphoid population
spellingShingle S. Tkachuk
O. Tkachuk
O. Denysenko
O. Yasinska
O. Garvasiuk
Age features of the thymocite RNA response in the thymus structural and functional areas to blood circulation disorders in the pool of carotic arteries in rats
Journal of Education, Health and Sport
incomplete global cerebral ischemia-reperfusion
cells of the thymus lymphoid population
title Age features of the thymocite RNA response in the thymus structural and functional areas to blood circulation disorders in the pool of carotic arteries in rats
title_full Age features of the thymocite RNA response in the thymus structural and functional areas to blood circulation disorders in the pool of carotic arteries in rats
title_fullStr Age features of the thymocite RNA response in the thymus structural and functional areas to blood circulation disorders in the pool of carotic arteries in rats
title_full_unstemmed Age features of the thymocite RNA response in the thymus structural and functional areas to blood circulation disorders in the pool of carotic arteries in rats
title_short Age features of the thymocite RNA response in the thymus structural and functional areas to blood circulation disorders in the pool of carotic arteries in rats
title_sort age features of the thymocite rna response in the thymus structural and functional areas to blood circulation disorders in the pool of carotic arteries in rats
topic incomplete global cerebral ischemia-reperfusion
cells of the thymus lymphoid population
url https://apcz.umk.pl/JEHS/article/view/46639
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