Diffusion sensitivity enhancement filter for raw DWIs

In this study, a post‐processing filter to enhance diffusion sensitivity, resulting in larger intensity changes in regions with the abrupt transition of local diffusivity in raw diffusion weighted image (DWI) volumes. Weights computed using a non‐linear three‐dimensional neighbourhood operation are...

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Main Authors: Joshin John Mathew, Alex James, Chandrasekhar Kesavadas, Joseph Suresh Paul
Format: Article
Language:English
Published: Wiley 2018-10-01
Series:IET Computer Vision
Subjects:
Online Access:https://doi.org/10.1049/iet-cvi.2018.5213
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author Joshin John Mathew
Alex James
Chandrasekhar Kesavadas
Joseph Suresh Paul
author_facet Joshin John Mathew
Alex James
Chandrasekhar Kesavadas
Joseph Suresh Paul
author_sort Joshin John Mathew
collection DOAJ
description In this study, a post‐processing filter to enhance diffusion sensitivity, resulting in larger intensity changes in regions with the abrupt transition of local diffusivity in raw diffusion weighted image (DWI) volumes. Weights computed using a non‐linear three‐dimensional neighbourhood operation are assigned to each voxel within the neighbourhood, with the weighted average representative of the enhanced DWI. The processed images exhibit better distinction among regions with differing levels of physical diffusion. While the resulting improvements in diffusion sensitivity are highlighted with the help of colour maps, parametric maps, and tractography, implications of the filtering process to recover missing information is illustrated in terms of ability to restore portions of fibre tracts which are otherwise absent in the unprocessed diffusion tensor imaging. Quantitative evaluation of the filtering process is performed using a metric representative of the estimated b‐value, which is the consolidation machine parameters used for DWI acquisition.
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spelling doaj.art-912620eb11ba4382b9a16535cb551ee72023-09-15T09:52:03ZengWileyIET Computer Vision1751-96321751-96402018-10-0112795095610.1049/iet-cvi.2018.5213Diffusion sensitivity enhancement filter for raw DWIsJoshin John Mathew0Alex James1Chandrasekhar Kesavadas2Joseph Suresh Paul3Computer Vision TeamARS Traffic and Transport TechnologyTrivandrumIndiaDepartment of Electrical and Computer EngineeringNazarbayev UniversityAstanaKazakhstanDepartment of Imaging Sciences and Interventional RadiologySCTIMSTTrivandrumIndiaMedical Image Computing and Signal Processing GroupIIITM‐KTrivandrumIndiaIn this study, a post‐processing filter to enhance diffusion sensitivity, resulting in larger intensity changes in regions with the abrupt transition of local diffusivity in raw diffusion weighted image (DWI) volumes. Weights computed using a non‐linear three‐dimensional neighbourhood operation are assigned to each voxel within the neighbourhood, with the weighted average representative of the enhanced DWI. The processed images exhibit better distinction among regions with differing levels of physical diffusion. While the resulting improvements in diffusion sensitivity are highlighted with the help of colour maps, parametric maps, and tractography, implications of the filtering process to recover missing information is illustrated in terms of ability to restore portions of fibre tracts which are otherwise absent in the unprocessed diffusion tensor imaging. Quantitative evaluation of the filtering process is performed using a metric representative of the estimated b‐value, which is the consolidation machine parameters used for DWI acquisition.https://doi.org/10.1049/iet-cvi.2018.5213nonlinear three-dimensional neighbourhood operationweighted average representativeenhanced DWIprocessed imagesphysical diffusionresulting improvements
spellingShingle Joshin John Mathew
Alex James
Chandrasekhar Kesavadas
Joseph Suresh Paul
Diffusion sensitivity enhancement filter for raw DWIs
IET Computer Vision
nonlinear three-dimensional neighbourhood operation
weighted average representative
enhanced DWI
processed images
physical diffusion
resulting improvements
title Diffusion sensitivity enhancement filter for raw DWIs
title_full Diffusion sensitivity enhancement filter for raw DWIs
title_fullStr Diffusion sensitivity enhancement filter for raw DWIs
title_full_unstemmed Diffusion sensitivity enhancement filter for raw DWIs
title_short Diffusion sensitivity enhancement filter for raw DWIs
title_sort diffusion sensitivity enhancement filter for raw dwis
topic nonlinear three-dimensional neighbourhood operation
weighted average representative
enhanced DWI
processed images
physical diffusion
resulting improvements
url https://doi.org/10.1049/iet-cvi.2018.5213
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AT chandrasekharkesavadas diffusionsensitivityenhancementfilterforrawdwis
AT josephsureshpaul diffusionsensitivityenhancementfilterforrawdwis