Cytotoxic effect of bionanocatalysts evaluated by diffuse reflectance spectroscopy in an in vivo model of hepatocellular carcinoma
Given the absence of effective and selective treatments for hepatocellular carcinoma (HCC), the antitumor effect of novel bionanocatalysts was evaluated in two different tissues (liver and lung) of a rat model with HCC using Diffuse Reflectance Spectroscopy. The spectra obtained showed a significant...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | Results in Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715623001339 |
| _version_ | 1827920658255839232 |
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| author | Francisco J. Padilla-Godínez Paola Ramírez Roberto Cruz Iván Sánchez José M. de la Rosa Tessy López-Goerne |
| author_facet | Francisco J. Padilla-Godínez Paola Ramírez Roberto Cruz Iván Sánchez José M. de la Rosa Tessy López-Goerne |
| author_sort | Francisco J. Padilla-Godínez |
| collection | DOAJ |
| description | Given the absence of effective and selective treatments for hepatocellular carcinoma (HCC), the antitumor effect of novel bionanocatalysts was evaluated in two different tissues (liver and lung) of a rat model with HCC using Diffuse Reflectance Spectroscopy. The spectra obtained showed a significant decrease in signal intensity in the presence of tumor tissues with respect to healthy tissue. An increase in signal intensity was observed in diseased rats treated with bionanocatalysts, suggesting their antitumor effect in terms of tumor tissue reduction with respect to the diseased control. |
| first_indexed | 2024-03-13T04:13:41Z |
| format | Article |
| id | doaj.art-9126c26144944c0692c9276478be8124 |
| institution | Directory Open Access Journal |
| issn | 2211-7156 |
| language | English |
| last_indexed | 2024-03-13T04:13:41Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Results in Chemistry |
| spelling | doaj.art-9126c26144944c0692c9276478be81242023-06-21T06:52:28ZengElsevierResults in Chemistry2211-71562023-01-015100894Cytotoxic effect of bionanocatalysts evaluated by diffuse reflectance spectroscopy in an in vivo model of hepatocellular carcinomaFrancisco J. Padilla-Godínez0Paola Ramírez1Roberto Cruz2Iván Sánchez3José M. de la Rosa4Tessy López-Goerne5Nanotechnology and Nanomedicine Laboratory, Department of Health Care, Metropolitan Autonomous University – Xochimilco, Mexico City 04960, MexicoNanotechnology and Nanomedicine Laboratory, Department of Health Care, Metropolitan Autonomous University – Xochimilco, Mexico City 04960, Mexico; Corresponding authors.School of Mechanical and Electrical Engineering – Zacatenco, National Polytechnic Institute, Mexico City 07738, MexicoSchool of Mechanical and Electrical Engineering – Zacatenco, National Polytechnic Institute, Mexico City 07738, MexicoInterdisciplinary Professional Unit in Engineering and Advanced Technology, National Polytechnic Institute, Mexico City 07340, MexicoNanotechnology and Nanomedicine Laboratory, Department of Health Care, Metropolitan Autonomous University – Xochimilco, Mexico City 04960, Mexico; Corresponding authors.Given the absence of effective and selective treatments for hepatocellular carcinoma (HCC), the antitumor effect of novel bionanocatalysts was evaluated in two different tissues (liver and lung) of a rat model with HCC using Diffuse Reflectance Spectroscopy. The spectra obtained showed a significant decrease in signal intensity in the presence of tumor tissues with respect to healthy tissue. An increase in signal intensity was observed in diseased rats treated with bionanocatalysts, suggesting their antitumor effect in terms of tumor tissue reduction with respect to the diseased control.http://www.sciencedirect.com/science/article/pii/S2211715623001339BionanocatalystsCytotoxicityDiffuse reflectance spectroscopyHepatocellular carcinoma |
| spellingShingle | Francisco J. Padilla-Godínez Paola Ramírez Roberto Cruz Iván Sánchez José M. de la Rosa Tessy López-Goerne Cytotoxic effect of bionanocatalysts evaluated by diffuse reflectance spectroscopy in an in vivo model of hepatocellular carcinoma Results in Chemistry Bionanocatalysts Cytotoxicity Diffuse reflectance spectroscopy Hepatocellular carcinoma |
| title | Cytotoxic effect of bionanocatalysts evaluated by diffuse reflectance spectroscopy in an in vivo model of hepatocellular carcinoma |
| title_full | Cytotoxic effect of bionanocatalysts evaluated by diffuse reflectance spectroscopy in an in vivo model of hepatocellular carcinoma |
| title_fullStr | Cytotoxic effect of bionanocatalysts evaluated by diffuse reflectance spectroscopy in an in vivo model of hepatocellular carcinoma |
| title_full_unstemmed | Cytotoxic effect of bionanocatalysts evaluated by diffuse reflectance spectroscopy in an in vivo model of hepatocellular carcinoma |
| title_short | Cytotoxic effect of bionanocatalysts evaluated by diffuse reflectance spectroscopy in an in vivo model of hepatocellular carcinoma |
| title_sort | cytotoxic effect of bionanocatalysts evaluated by diffuse reflectance spectroscopy in an in vivo model of hepatocellular carcinoma |
| topic | Bionanocatalysts Cytotoxicity Diffuse reflectance spectroscopy Hepatocellular carcinoma |
| url | http://www.sciencedirect.com/science/article/pii/S2211715623001339 |
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