Estrogen Receptor Alpha Gene (ESR1) Facilitates Th2-immune Response and Enhances Th2 Cytokines in Experimental Atopic Dermatitis Mice

Estrogen Receptor Alpha Gene (ESR1) Facilitates Th2-immune Response and Enhances Th2 Cytokines in Experimental Atopic Dermatitis Mice

Background: Molecular markers are involved in atopic dermatitis (AD) pathogenesis. The estrogen receptor (ESR)-1 gene, encoding ERα, is reported to express aberrantly in AD patients.Objective: To detect the biological functions of ESR1 in 2,4 dinitrochlorobenzene (DNCB)-treated mice.Methods: The DNC...

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Bibliographic Details
Main Authors: Jianrong Niu, Hui Zhou, Rong Tian, Xudong Wang
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2023-06-01
Series:Iranian Journal of Immunology
Subjects:
antagonist
atopic dermatitis
esr1
inflammatory cytokines
mice
Online Access:https://iji.sums.ac.ir/article_49308_75a0c1dbc99a8103f3930b8053d19f1c.pdf

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