Turnover of strain-level diversity modulates functional traits in the honeybee gut microbiome between nurses and foragers
Abstract Background Strain-level diversity is widespread among bacterial species and can expand the functional potential of natural microbial communities. However, to what extent communities undergo consistent shifts in strain composition in response to environmental/host changes is less well unders...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-12-01
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| Series: | Genome Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13059-023-03131-4 |
| _version_ | 1797397959218823168 |
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| author | Gilles L. C. Baud Aiswarya Prasad Kirsten M. Ellegaard Philipp Engel |
| author_facet | Gilles L. C. Baud Aiswarya Prasad Kirsten M. Ellegaard Philipp Engel |
| author_sort | Gilles L. C. Baud |
| collection | DOAJ |
| description | Abstract Background Strain-level diversity is widespread among bacterial species and can expand the functional potential of natural microbial communities. However, to what extent communities undergo consistent shifts in strain composition in response to environmental/host changes is less well understood. Results Here, we used shotgun metagenomics to compare the gut microbiota of two behavioral states of the Western honeybee (Apis mellifera), namely nurse and forager bees. While their gut microbiota is composed of the same bacterial species, we detect consistent changes in strain-level composition between nurses and foragers. Single nucleotide variant profiles of predominant bacterial species cluster by behavioral state. Moreover, we identify strain-specific gene content related to nutrient utilization, vitamin biosynthesis, and cell–cell interactions specifically associated with the two behavioral states. Conclusions Our findings show that strain-level diversity in host-associated communities can undergo consistent changes in response to host behavioral changes modulating the functional potential of the community. |
| first_indexed | 2024-03-09T01:17:44Z |
| format | Article |
| id | doaj.art-912b22312b8942e7a6b1f87091ac3565 |
| institution | Directory Open Access Journal |
| issn | 1474-760X |
| language | English |
| last_indexed | 2024-03-09T01:17:44Z |
| publishDate | 2023-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Genome Biology |
| spelling | doaj.art-912b22312b8942e7a6b1f87091ac35652023-12-10T12:20:53ZengBMCGenome Biology1474-760X2023-12-0124112110.1186/s13059-023-03131-4Turnover of strain-level diversity modulates functional traits in the honeybee gut microbiome between nurses and foragersGilles L. C. Baud0Aiswarya Prasad1Kirsten M. Ellegaard2Philipp Engel3Department of Fundamental Microbiology, University of LausanneDepartment of Fundamental Microbiology, University of LausanneDepartment of Fundamental Microbiology, University of LausanneDepartment of Fundamental Microbiology, University of LausanneAbstract Background Strain-level diversity is widespread among bacterial species and can expand the functional potential of natural microbial communities. However, to what extent communities undergo consistent shifts in strain composition in response to environmental/host changes is less well understood. Results Here, we used shotgun metagenomics to compare the gut microbiota of two behavioral states of the Western honeybee (Apis mellifera), namely nurse and forager bees. While their gut microbiota is composed of the same bacterial species, we detect consistent changes in strain-level composition between nurses and foragers. Single nucleotide variant profiles of predominant bacterial species cluster by behavioral state. Moreover, we identify strain-specific gene content related to nutrient utilization, vitamin biosynthesis, and cell–cell interactions specifically associated with the two behavioral states. Conclusions Our findings show that strain-level diversity in host-associated communities can undergo consistent changes in response to host behavioral changes modulating the functional potential of the community.https://doi.org/10.1186/s13059-023-03131-4MetagenomicsGut microbiotaStrain diversityHoney beeSymbiosisSocial insects |
| spellingShingle | Gilles L. C. Baud Aiswarya Prasad Kirsten M. Ellegaard Philipp Engel Turnover of strain-level diversity modulates functional traits in the honeybee gut microbiome between nurses and foragers Genome Biology Metagenomics Gut microbiota Strain diversity Honey bee Symbiosis Social insects |
| title | Turnover of strain-level diversity modulates functional traits in the honeybee gut microbiome between nurses and foragers |
| title_full | Turnover of strain-level diversity modulates functional traits in the honeybee gut microbiome between nurses and foragers |
| title_fullStr | Turnover of strain-level diversity modulates functional traits in the honeybee gut microbiome between nurses and foragers |
| title_full_unstemmed | Turnover of strain-level diversity modulates functional traits in the honeybee gut microbiome between nurses and foragers |
| title_short | Turnover of strain-level diversity modulates functional traits in the honeybee gut microbiome between nurses and foragers |
| title_sort | turnover of strain level diversity modulates functional traits in the honeybee gut microbiome between nurses and foragers |
| topic | Metagenomics Gut microbiota Strain diversity Honey bee Symbiosis Social insects |
| url | https://doi.org/10.1186/s13059-023-03131-4 |
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