Case report: Applicability of breastfeeding the child of a patient with kidney failure with replacement therapy
This case report highlights the benefit or harm of breastfeeding in a patient with Kidney Failure with Replacement Therapy (KFRT) undergoing program hemodialysis. This is a unique clinical case, as pregnancy and successful delivery are rare in this group of females. With a favorable outcome, the pos...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-02-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1098324/full |
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| author | Elena V. Kondakova Anastasia E. Filat’eva Nadezhda A. Lobanova Nadezhda A. Lobanova Egor I. Nagaev Ruslan M. Sarimov Sergey V. Gudkov Maria V. Vedunova |
| author_facet | Elena V. Kondakova Anastasia E. Filat’eva Nadezhda A. Lobanova Nadezhda A. Lobanova Egor I. Nagaev Ruslan M. Sarimov Sergey V. Gudkov Maria V. Vedunova |
| author_sort | Elena V. Kondakova |
| collection | DOAJ |
| description | This case report highlights the benefit or harm of breastfeeding in a patient with Kidney Failure with Replacement Therapy (KFRT) undergoing program hemodialysis. This is a unique clinical case, as pregnancy and successful delivery are rare in this group of females. With a favorable outcome, the possibility of breastfeeding is especially relevant for doctors and the mother. The patient was a 31-year-old female who was diagnosed in 2017 with end-stage renal disease associated with chronic glomerulonephritis. Against the background of hemodialysis, pregnancy, accompanied by polyhydramnios, anemia, and secondary arterial hypertension, occurred in 2021. At 37 weeks, a healthy, full-term baby girl was born, and breastfeeding was started. In this study, we conducted a detailed analysis of toxic substances and immunologically significant proteins using high-tech analysis methods. In addition, we studied different portions of milk before and after hemodialysis at different time intervals. After a wide range of experiments, our study did not reveal an optimal time interval for breastfeeding a baby. Despite the decrease in the level of the major uremic toxins 4 h after the hemodialysis procedure, their level remained high. In addition, the content of nutrients did not reach acceptable limits and the immune status was characterized as pro-inflammatory. In our opinion, breastfeeding is not advisable for this group of patients since the concentration of nutrients is low, and the content of toxic substances exceeds the permissible limits. In this clinical case, the patient decided to stop breastfeeding one month after delivery due to insufficient breast milk and the inability to express it in a certain period of time. |
| first_indexed | 2024-04-10T16:03:53Z |
| format | Article |
| id | doaj.art-912d3cc736f242f8b389d590db4a1884 |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-10T16:03:53Z |
| publishDate | 2023-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-912d3cc736f242f8b389d590db4a18842023-02-10T06:48:13ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-02-011010.3389/fmed.2023.10983241098324Case report: Applicability of breastfeeding the child of a patient with kidney failure with replacement therapyElena V. Kondakova0Anastasia E. Filat’eva1Nadezhda A. Lobanova2Nadezhda A. Lobanova3Egor I. Nagaev4Ruslan M. Sarimov5Sergey V. Gudkov6Maria V. Vedunova7Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, Nizhny Novgorod, RussiaInstitute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, Nizhny Novgorod, RussiaInstitute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, Nizhny Novgorod, RussiaBranch FESFARM NN, Nizhny Novgorod, RussiaProkhorov General Physics Institute of the Russian Academy of Sciences, Moscow, RussiaProkhorov General Physics Institute of the Russian Academy of Sciences, Moscow, RussiaProkhorov General Physics Institute of the Russian Academy of Sciences, Moscow, RussiaInstitute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, Nizhny Novgorod, RussiaThis case report highlights the benefit or harm of breastfeeding in a patient with Kidney Failure with Replacement Therapy (KFRT) undergoing program hemodialysis. This is a unique clinical case, as pregnancy and successful delivery are rare in this group of females. With a favorable outcome, the possibility of breastfeeding is especially relevant for doctors and the mother. The patient was a 31-year-old female who was diagnosed in 2017 with end-stage renal disease associated with chronic glomerulonephritis. Against the background of hemodialysis, pregnancy, accompanied by polyhydramnios, anemia, and secondary arterial hypertension, occurred in 2021. At 37 weeks, a healthy, full-term baby girl was born, and breastfeeding was started. In this study, we conducted a detailed analysis of toxic substances and immunologically significant proteins using high-tech analysis methods. In addition, we studied different portions of milk before and after hemodialysis at different time intervals. After a wide range of experiments, our study did not reveal an optimal time interval for breastfeeding a baby. Despite the decrease in the level of the major uremic toxins 4 h after the hemodialysis procedure, their level remained high. In addition, the content of nutrients did not reach acceptable limits and the immune status was characterized as pro-inflammatory. In our opinion, breastfeeding is not advisable for this group of patients since the concentration of nutrients is low, and the content of toxic substances exceeds the permissible limits. In this clinical case, the patient decided to stop breastfeeding one month after delivery due to insufficient breast milk and the inability to express it in a certain period of time.https://www.frontiersin.org/articles/10.3389/fmed.2023.1098324/fullcase reportbreastfeedingimmunologyKidney Failure with Replacement Therapy (KFRT)biochemistrymolecular physics |
| spellingShingle | Elena V. Kondakova Anastasia E. Filat’eva Nadezhda A. Lobanova Nadezhda A. Lobanova Egor I. Nagaev Ruslan M. Sarimov Sergey V. Gudkov Maria V. Vedunova Case report: Applicability of breastfeeding the child of a patient with kidney failure with replacement therapy Frontiers in Medicine case report breastfeeding immunology Kidney Failure with Replacement Therapy (KFRT) biochemistry molecular physics |
| title | Case report: Applicability of breastfeeding the child of a patient with kidney failure with replacement therapy |
| title_full | Case report: Applicability of breastfeeding the child of a patient with kidney failure with replacement therapy |
| title_fullStr | Case report: Applicability of breastfeeding the child of a patient with kidney failure with replacement therapy |
| title_full_unstemmed | Case report: Applicability of breastfeeding the child of a patient with kidney failure with replacement therapy |
| title_short | Case report: Applicability of breastfeeding the child of a patient with kidney failure with replacement therapy |
| title_sort | case report applicability of breastfeeding the child of a patient with kidney failure with replacement therapy |
| topic | case report breastfeeding immunology Kidney Failure with Replacement Therapy (KFRT) biochemistry molecular physics |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2023.1098324/full |
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