EPHB6 mutation induces cell adhesion-mediated paclitaxel resistance via EPHA2 and CDH11 expression

Cancer: Gene mutation spurs drug resistance Mutations in a gene linked to cancer growth also underpin resistance to a common chemotherapy drug. Hyun Goo Woo and colleagues from Ajou University in Suwon, South Korea, analyzed a large database of genetic information on more than 1,000 human cancer cel...

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Bibliographic Details
Main Authors: Sarah Yoon, Ji-Hye Choi, Sung Joo Kim, Eun-Ju Lee, Masaud Shah, Sangdun Choi, Hyun Goo Woo
Format: Article
Language:English
Published: Nature Publishing Group 2019-06-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-019-0261-z