MetaStorm: A Public Resource for Customizable Metagenomics Annotation.
Metagenomics is a trending research area, calling for the need to analyze large quantities of data generated from next generation DNA sequencing technologies. The need to store, retrieve, analyze, share, and visualize such data challenges current online computational systems. Interpretation and anno...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2016-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC5025195?pdf=render |
| _version_ | 1818538064319873024 |
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| author | Gustavo Arango-Argoty Gargi Singh Lenwood S Heath Amy Pruden Weidong Xiao Liqing Zhang |
| author_facet | Gustavo Arango-Argoty Gargi Singh Lenwood S Heath Amy Pruden Weidong Xiao Liqing Zhang |
| author_sort | Gustavo Arango-Argoty |
| collection | DOAJ |
| description | Metagenomics is a trending research area, calling for the need to analyze large quantities of data generated from next generation DNA sequencing technologies. The need to store, retrieve, analyze, share, and visualize such data challenges current online computational systems. Interpretation and annotation of specific information is especially a challenge for metagenomic data sets derived from environmental samples, because current annotation systems only offer broad classification of microbial diversity and function. Moreover, existing resources are not configured to readily address common questions relevant to environmental systems. Here we developed a new online user-friendly metagenomic analysis server called MetaStorm (http://bench.cs.vt.edu/MetaStorm/), which facilitates customization of computational analysis for metagenomic data sets. Users can upload their own reference databases to tailor the metagenomics annotation to focus on various taxonomic and functional gene markers of interest. MetaStorm offers two major analysis pipelines: an assembly-based annotation pipeline and the standard read annotation pipeline used by existing web servers. These pipelines can be selected individually or together. Overall, MetaStorm provides enhanced interactive visualization to allow researchers to explore and manipulate taxonomy and functional annotation at various levels of resolution. |
| first_indexed | 2024-12-11T18:58:46Z |
| format | Article |
| id | doaj.art-912f09a8da2b49179ce21b1b7cb88262 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-11T18:58:46Z |
| publishDate | 2016-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-912f09a8da2b49179ce21b1b7cb882622022-12-22T00:54:04ZengPublic Library of Science (PLoS)PLoS ONE1932-62032016-01-01119e016244210.1371/journal.pone.0162442MetaStorm: A Public Resource for Customizable Metagenomics Annotation.Gustavo Arango-ArgotyGargi SinghLenwood S HeathAmy PrudenWeidong XiaoLiqing ZhangMetagenomics is a trending research area, calling for the need to analyze large quantities of data generated from next generation DNA sequencing technologies. The need to store, retrieve, analyze, share, and visualize such data challenges current online computational systems. Interpretation and annotation of specific information is especially a challenge for metagenomic data sets derived from environmental samples, because current annotation systems only offer broad classification of microbial diversity and function. Moreover, existing resources are not configured to readily address common questions relevant to environmental systems. Here we developed a new online user-friendly metagenomic analysis server called MetaStorm (http://bench.cs.vt.edu/MetaStorm/), which facilitates customization of computational analysis for metagenomic data sets. Users can upload their own reference databases to tailor the metagenomics annotation to focus on various taxonomic and functional gene markers of interest. MetaStorm offers two major analysis pipelines: an assembly-based annotation pipeline and the standard read annotation pipeline used by existing web servers. These pipelines can be selected individually or together. Overall, MetaStorm provides enhanced interactive visualization to allow researchers to explore and manipulate taxonomy and functional annotation at various levels of resolution.http://europepmc.org/articles/PMC5025195?pdf=render |
| spellingShingle | Gustavo Arango-Argoty Gargi Singh Lenwood S Heath Amy Pruden Weidong Xiao Liqing Zhang MetaStorm: A Public Resource for Customizable Metagenomics Annotation. PLoS ONE |
| title | MetaStorm: A Public Resource for Customizable Metagenomics Annotation. |
| title_full | MetaStorm: A Public Resource for Customizable Metagenomics Annotation. |
| title_fullStr | MetaStorm: A Public Resource for Customizable Metagenomics Annotation. |
| title_full_unstemmed | MetaStorm: A Public Resource for Customizable Metagenomics Annotation. |
| title_short | MetaStorm: A Public Resource for Customizable Metagenomics Annotation. |
| title_sort | metastorm a public resource for customizable metagenomics annotation |
| url | http://europepmc.org/articles/PMC5025195?pdf=render |
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