Replicability of proton MR spectroscopic imaging findings in mild traumatic brain injury: Implications for clinical applications

Replicability of proton MR spectroscopic imaging findings in mild traumatic brain injury: Implications for clinical applications

Purpose: Proton magnetic resonance spectroscopy (1H MRS) offers biomarkers of metabolic damage after mild traumatic brain injury (mTBI), but a lack of replicability studies hampers clinical translation. In a conceptual replication study design, the results reported in four previous publications were...

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Bibliographic Details
Main Authors: Anna M. Chen, Teresa Gerhalter, Seena Dehkharghani, Rosemary Peralta, Mia Gajdošík, Martin Gajdošík, Mickael Tordjman, Julia Zabludovsky, Sulaiman Sheriff, Sinyeob Ahn, James S. Babb, Tamara Bushnik, Alejandro Zarate, Jonathan M. Silver, Brian S. Im, Stephen P. Wall, Guillaume Madelin, Ivan I. Kirov
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:NeuroImage: Clinical
Subjects:
Replicability
Mild traumatic brain injury (mTBI)
MR spectroscopic imaging (MRSI)
Quantitative MR
Linear regression
Glasgow Outcome Scale Extended (GOSE)
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158223000141

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