Management of Gastrointestinal Neuroendocrine Tumors
Neuroendocrine neoplasms (NENs) are derived from neuroendocrine cell system and can have benign or malignant characteristics. They are rare tumors, but have been increasing in incidence over the past 40 years. Patients with NENs may develop symptoms due to primary tumor invasion, metastasis, or from...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2019-10-01
|
| Series: | Clinical Medicine Insights: Endocrinology and Diabetes |
| Online Access: | https://doi.org/10.1177/1179551419884058 |
| _version_ | 1811339572190117888 |
|---|---|
| author | Rongzhi Wang Rui Zheng-Pywell H Alexander Chen James A Bibb Herbert Chen J Bart Rose |
| author_facet | Rongzhi Wang Rui Zheng-Pywell H Alexander Chen James A Bibb Herbert Chen J Bart Rose |
| author_sort | Rongzhi Wang |
| collection | DOAJ |
| description | Neuroendocrine neoplasms (NENs) are derived from neuroendocrine cell system and can have benign or malignant characteristics. They are rare tumors, but have been increasing in incidence over the past 40 years. Patients with NENs may develop symptoms due to primary tumor invasion, metastasis, or from secretion of hormonally active tumor substances. Multiple imaging modalities are used for diagnosis and staging, including specialty scans such as 111 In pentetreotide (Octreoscan) and 68 Gallium-DOTATATE, along with endoscopy, endoscopic ultrasound, and biochemical marker testing. Treatment involves both surgical approach, for both primary and metastatic lesions, as well as medical management for symptom management and disease progression. This article will review the current clinical knowledge regarding the diagnosis, treatment, and prognosis of these fascinating neoplasms and the associated hormonal syndromes. |
| first_indexed | 2024-04-13T18:28:49Z |
| format | Article |
| id | doaj.art-91325df417674fb4ba29b69afef1cf2e |
| institution | Directory Open Access Journal |
| issn | 1179-5514 |
| language | English |
| last_indexed | 2024-04-13T18:28:49Z |
| publishDate | 2019-10-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Clinical Medicine Insights: Endocrinology and Diabetes |
| spelling | doaj.art-91325df417674fb4ba29b69afef1cf2e2022-12-22T02:35:10ZengSAGE PublishingClinical Medicine Insights: Endocrinology and Diabetes1179-55142019-10-011210.1177/1179551419884058Management of Gastrointestinal Neuroendocrine TumorsRongzhi WangRui Zheng-PywellH Alexander ChenJames A BibbHerbert ChenJ Bart RoseNeuroendocrine neoplasms (NENs) are derived from neuroendocrine cell system and can have benign or malignant characteristics. They are rare tumors, but have been increasing in incidence over the past 40 years. Patients with NENs may develop symptoms due to primary tumor invasion, metastasis, or from secretion of hormonally active tumor substances. Multiple imaging modalities are used for diagnosis and staging, including specialty scans such as 111 In pentetreotide (Octreoscan) and 68 Gallium-DOTATATE, along with endoscopy, endoscopic ultrasound, and biochemical marker testing. Treatment involves both surgical approach, for both primary and metastatic lesions, as well as medical management for symptom management and disease progression. This article will review the current clinical knowledge regarding the diagnosis, treatment, and prognosis of these fascinating neoplasms and the associated hormonal syndromes.https://doi.org/10.1177/1179551419884058 |
| spellingShingle | Rongzhi Wang Rui Zheng-Pywell H Alexander Chen James A Bibb Herbert Chen J Bart Rose Management of Gastrointestinal Neuroendocrine Tumors Clinical Medicine Insights: Endocrinology and Diabetes |
| title | Management of Gastrointestinal Neuroendocrine Tumors |
| title_full | Management of Gastrointestinal Neuroendocrine Tumors |
| title_fullStr | Management of Gastrointestinal Neuroendocrine Tumors |
| title_full_unstemmed | Management of Gastrointestinal Neuroendocrine Tumors |
| title_short | Management of Gastrointestinal Neuroendocrine Tumors |
| title_sort | management of gastrointestinal neuroendocrine tumors |
| url | https://doi.org/10.1177/1179551419884058 |
| work_keys_str_mv | AT rongzhiwang managementofgastrointestinalneuroendocrinetumors AT ruizhengpywell managementofgastrointestinalneuroendocrinetumors AT halexanderchen managementofgastrointestinalneuroendocrinetumors AT jamesabibb managementofgastrointestinalneuroendocrinetumors AT herbertchen managementofgastrointestinalneuroendocrinetumors AT jbartrose managementofgastrointestinalneuroendocrinetumors |