Polymorphous adenocarcinoma of the parotid – An uncommon site of occurrence

Polymorphous low-grade adenocarcinoma is a neoplasm of the minor salivary glands and is malignant in origin but is indolent in nature. Currently, this neoplasm is documented and known as polymorphous adenocarcinoma (PAC) by WHO Classification of Salivary Gland Tumors (2017). Of all the salivary neop...

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Päätekijät: Prabhat Mahato, Chhanda Das, Ankita Pranab Mandal, Madhumita Mukhopadhyay
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: Wolters Kluwer Medknow Publications 2022-01-01
Sarja:International Journal of Advanced Medical and Health Research
Aiheet:
Linkit:http://www.ijamhrjournal.org/article.asp?issn=2349-4220;year=2022;volume=9;issue=1;spage=52;epage=54;aulast=Mahato
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author Prabhat Mahato
Chhanda Das
Ankita Pranab Mandal
Madhumita Mukhopadhyay
author_facet Prabhat Mahato
Chhanda Das
Ankita Pranab Mandal
Madhumita Mukhopadhyay
author_sort Prabhat Mahato
collection DOAJ
description Polymorphous low-grade adenocarcinoma is a neoplasm of the minor salivary glands and is malignant in origin but is indolent in nature. Currently, this neoplasm is documented and known as polymorphous adenocarcinoma (PAC) by WHO Classification of Salivary Gland Tumors (2017). Of all the salivary neoplasms, minor salivary gland neoplasm accounts for 9%–23%. Very rarely, it involves major salivary glands such as parotid, submandibular, and sublingual in <5% cases. It may develop either de novo or from pleomorphic adenoma. PAC mimics some benign as well as malignant neoplasms. Histopathological features alone cannot diagnose PAC due to the overlapping features with other neoplasms, and so immunohistochemistry is essential to confirm the diagnosis and hence aids in the proper management of PAC. We report a case of PAC arising from parotid gland in a 52-year-old male treated with facial nerve preservation.
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spelling doaj.art-91343f72077f4d54b1a6e4d8f0a76f5c2022-12-22T03:00:20ZengWolters Kluwer Medknow PublicationsInternational Journal of Advanced Medical and Health Research2349-42202350-02982022-01-0191525410.4103/ijamr.ijamr_207_21Polymorphous adenocarcinoma of the parotid – An uncommon site of occurrencePrabhat MahatoChhanda DasAnkita Pranab MandalMadhumita MukhopadhyayPolymorphous low-grade adenocarcinoma is a neoplasm of the minor salivary glands and is malignant in origin but is indolent in nature. Currently, this neoplasm is documented and known as polymorphous adenocarcinoma (PAC) by WHO Classification of Salivary Gland Tumors (2017). Of all the salivary neoplasms, minor salivary gland neoplasm accounts for 9%–23%. Very rarely, it involves major salivary glands such as parotid, submandibular, and sublingual in <5% cases. It may develop either de novo or from pleomorphic adenoma. PAC mimics some benign as well as malignant neoplasms. Histopathological features alone cannot diagnose PAC due to the overlapping features with other neoplasms, and so immunohistochemistry is essential to confirm the diagnosis and hence aids in the proper management of PAC. We report a case of PAC arising from parotid gland in a 52-year-old male treated with facial nerve preservation.http://www.ijamhrjournal.org/article.asp?issn=2349-4220;year=2022;volume=9;issue=1;spage=52;epage=54;aulast=Mahatoimmunohistochemistryparotidpolymorphous adenocarcinomasalivary gland
spellingShingle Prabhat Mahato
Chhanda Das
Ankita Pranab Mandal
Madhumita Mukhopadhyay
Polymorphous adenocarcinoma of the parotid – An uncommon site of occurrence
International Journal of Advanced Medical and Health Research
immunohistochemistry
parotid
polymorphous adenocarcinoma
salivary gland
title Polymorphous adenocarcinoma of the parotid – An uncommon site of occurrence
title_full Polymorphous adenocarcinoma of the parotid – An uncommon site of occurrence
title_fullStr Polymorphous adenocarcinoma of the parotid – An uncommon site of occurrence
title_full_unstemmed Polymorphous adenocarcinoma of the parotid – An uncommon site of occurrence
title_short Polymorphous adenocarcinoma of the parotid – An uncommon site of occurrence
title_sort polymorphous adenocarcinoma of the parotid an uncommon site of occurrence
topic immunohistochemistry
parotid
polymorphous adenocarcinoma
salivary gland
url http://www.ijamhrjournal.org/article.asp?issn=2349-4220;year=2022;volume=9;issue=1;spage=52;epage=54;aulast=Mahato
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AT ankitapranabmandal polymorphousadenocarcinomaoftheparotidanuncommonsiteofoccurrence
AT madhumitamukhopadhyay polymorphousadenocarcinomaoftheparotidanuncommonsiteofoccurrence