Selective YAP activation in Procr cells is essential for ovarian stem/progenitor expansion and epithelium repair

Selective YAP activation in Procr cells is essential for ovarian stem/progenitor expansion and epithelium repair

Ovarian surface epithelium (OSE) undergoes recurring ovulatory rupture and OSE stem cells rapidly generate new cells for the repair. How the stem cell activation is triggered by the rupture and promptly turns on proliferation is unclear. Our previous study has identified that Protein C Receptor (Pro...

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Bibliographic Details
Main Authors: Jingqiang Wang, Chunye Liu, Lingli He, Zhiyao Xie, Lanyue Bai, Wentao Yu, Zuoyun Wang, Yi Lu, Dong Gao, Junfen Fu, Lei Zhang, Yi Arial Zeng
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-03-01
Series:eLife
Subjects:
ovarian surface epithelium
ovulatory rupture repair
adult stem cells
YAP
Procr
Online Access:https://elifesciences.org/articles/75449

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