Microbiomics of Oral Biofilms: Driving The Future of Dental Research
Oral infectious diseases such as dental caries, periodontal disease, endodontic infections, oral candidiasis and peri-implantitis cause major health problems worldwide. All of these infectious diseases are associated with the biofilm growth mode of the oral pathogens. In the past, researchers often...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-09-01
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| Series: | Scientific Dental Journal |
| Online Access: | http://www.trijurnal.lemlit.trisakti.ac.id/index.php/dental/article/view/2089 |
| _version_ | 1819146106306560000 |
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| author | Chaminda Jayampath Seneviratne Tanujaa Suriyanarayanan |
| author_facet | Chaminda Jayampath Seneviratne Tanujaa Suriyanarayanan |
| author_sort | Chaminda Jayampath Seneviratne |
| collection | DOAJ |
| description | Oral infectious diseases such as dental caries, periodontal disease, endodontic infections, oral candidiasis and peri-implantitis cause major health problems worldwide. All of these infectious diseases are associated with the biofilm growth mode of the oral pathogens. In the past, researchers often attempted to examine the association of single pathogens with particular dental diseases such as in the case of Streptococcus mutans acting as an aetiological agent for dental caries and the so-called “red-complex” bacteria for periodontal disease. However, with the recent advent of OMICS biology techniques such as genomics, transcriptomics, proteomics, it is possible to gain new insights into the host-microbial interaction, microbial community structure and composition in the oral cavity. The new studies on oral microbiomics can unravel the facets of the aetiopathology of oral diseases as never seen before. This mini-review will provide an history and overview of some of the existing DNA sequencing platforms employed to study the microbiomics of oral biofilms and the exciting future ahead for dental research. |
| first_indexed | 2024-12-22T13:08:39Z |
| format | Article |
| id | doaj.art-913971a49aba412d96040c2b378e7af9 |
| institution | Directory Open Access Journal |
| issn | 2580-6548 2541-321X |
| language | English |
| last_indexed | 2024-12-22T13:08:39Z |
| publishDate | 2017-09-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Scientific Dental Journal |
| spelling | doaj.art-913971a49aba412d96040c2b378e7af92022-12-21T18:24:48ZengWolters Kluwer Medknow PublicationsScientific Dental Journal2580-65482541-321X2017-09-0111253010.26912/sdj.v1i1.20891745Microbiomics of Oral Biofilms: Driving The Future of Dental ResearchChaminda Jayampath Seneviratne0Tanujaa Suriyanarayanan1Discipline of Oral Sciences, Faculty of Dentistry, National University of SingaporeDiscipline of Oral Sciences, Faculty of Dentistry, National University of SingaporeOral infectious diseases such as dental caries, periodontal disease, endodontic infections, oral candidiasis and peri-implantitis cause major health problems worldwide. All of these infectious diseases are associated with the biofilm growth mode of the oral pathogens. In the past, researchers often attempted to examine the association of single pathogens with particular dental diseases such as in the case of Streptococcus mutans acting as an aetiological agent for dental caries and the so-called “red-complex” bacteria for periodontal disease. However, with the recent advent of OMICS biology techniques such as genomics, transcriptomics, proteomics, it is possible to gain new insights into the host-microbial interaction, microbial community structure and composition in the oral cavity. The new studies on oral microbiomics can unravel the facets of the aetiopathology of oral diseases as never seen before. This mini-review will provide an history and overview of some of the existing DNA sequencing platforms employed to study the microbiomics of oral biofilms and the exciting future ahead for dental research.http://www.trijurnal.lemlit.trisakti.ac.id/index.php/dental/article/view/2089 |
| spellingShingle | Chaminda Jayampath Seneviratne Tanujaa Suriyanarayanan Microbiomics of Oral Biofilms: Driving The Future of Dental Research Scientific Dental Journal |
| title | Microbiomics of Oral Biofilms: Driving The Future of Dental Research |
| title_full | Microbiomics of Oral Biofilms: Driving The Future of Dental Research |
| title_fullStr | Microbiomics of Oral Biofilms: Driving The Future of Dental Research |
| title_full_unstemmed | Microbiomics of Oral Biofilms: Driving The Future of Dental Research |
| title_short | Microbiomics of Oral Biofilms: Driving The Future of Dental Research |
| title_sort | microbiomics of oral biofilms driving the future of dental research |
| url | http://www.trijurnal.lemlit.trisakti.ac.id/index.php/dental/article/view/2089 |
| work_keys_str_mv | AT chamindajayampathseneviratne microbiomicsoforalbiofilmsdrivingthefutureofdentalresearch AT tanujaasuriyanarayanan microbiomicsoforalbiofilmsdrivingthefutureofdentalresearch |