Involvement of MIF in basement membrane damage in chronically UVB-exposed skin in mice.

Involvement of MIF in basement membrane damage in chronically UVB-exposed skin in mice.

Solar ultraviolet (UV) B radiation is known to induce matrix metalloproteinases (MMPs) that degrade collagen in the basement membrane. Macrophage migration inhibitory factor (MIF) is a pluripotent cytokine that plays an essential role in the pathophysiology of skin inflammation induced by UV irradia...

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Bibliographic Details
Main Authors: Yoko Yoshihisa, Osamu Norisugi, Kenji Matsunaga, Jun Nishihira, Tadamichi Shimizu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3931804?pdf=render

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