Phytotherapy and treatment of cystitis: current trends

The treatment of lower urinary tract infections, in particular cystitis, remains an urgent problem of modern medicine. The high prevalence of the disease, formation of resistant strains of cau­sative microorganisms, a change in microbiota, and a limited arsenal of antimicrobial agents lead to an ann...

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Main Author: D.D. Ivanov
Format: Article
Language:English
Published: Zaslavsky O.Yu. 2019-10-01
Series:Počki
Subjects:
Online Access:http://kidneys.zaslavsky.com.ua/article/view/185117
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author D.D. Ivanov
author_facet D.D. Ivanov
author_sort D.D. Ivanov
collection DOAJ
description The treatment of lower urinary tract infections, in particular cystitis, remains an urgent problem of modern medicine. The high prevalence of the disease, formation of resistant strains of cau­sative microorganisms, a change in microbiota, and a limited arsenal of antimicrobial agents lead to an annual change in recommendations for the rational treatment of cystitis. The latest recommendations of the European Association of Urology (2019) significantly limit the use of antibiotics, in particular fluoroquinolones, among which, in our opinion, 3rd generation cephalosporins in a three-day regimen remains a priority in the absence of intracellular pathogens. National experience indicates the widespread successful use of urinary antiseptics among modern nitrofurantoins, resistance to which is documented in a very limited number of people with cystitis. Given that cystitis occurs mainly in women, we consider it advisable to recommend nifuratel as a first-line drug for 5–7 days. It has a wide spectrum of action and is effective for both specific and non-specific vulvovaginitis and bacterial vaginosis, which is often a provoking factor for cystitis. Among the alternative over-the-counter drugs that successfully form the evidence base, one should note a phytoniring drug. To maintain the function and reduce the risk of exacerbation of inflammatory genitourinary system diseases — dietary supplements, those containing 36 mg A-type proanthocyanidin and methylthioninium chloride, prescribed for 10 days. These compounds, along with nifuratel, are also successfully used in the form of a prophylactic reduced dose once per night for one to six months.
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spelling doaj.art-913d80106a0945548faddc435469d7d12022-12-21T20:04:50ZengZaslavsky O.Yu.Počki2307-12572307-12652019-10-018419620010.22141/2307-1257.8.4.2019.185117185117Phytotherapy and treatment of cystitis: current trendsD.D. Ivanov0MD, PhD, Professor, Head of the Department of nephrology and renal replacement therapy, Shupyk National Medical Academy of Postgraduate Education, KyivThe treatment of lower urinary tract infections, in particular cystitis, remains an urgent problem of modern medicine. The high prevalence of the disease, formation of resistant strains of cau­sative microorganisms, a change in microbiota, and a limited arsenal of antimicrobial agents lead to an annual change in recommendations for the rational treatment of cystitis. The latest recommendations of the European Association of Urology (2019) significantly limit the use of antibiotics, in particular fluoroquinolones, among which, in our opinion, 3rd generation cephalosporins in a three-day regimen remains a priority in the absence of intracellular pathogens. National experience indicates the widespread successful use of urinary antiseptics among modern nitrofurantoins, resistance to which is documented in a very limited number of people with cystitis. Given that cystitis occurs mainly in women, we consider it advisable to recommend nifuratel as a first-line drug for 5–7 days. It has a wide spectrum of action and is effective for both specific and non-specific vulvovaginitis and bacterial vaginosis, which is often a provoking factor for cystitis. Among the alternative over-the-counter drugs that successfully form the evidence base, one should note a phytoniring drug. To maintain the function and reduce the risk of exacerbation of inflammatory genitourinary system diseases — dietary supplements, those containing 36 mg A-type proanthocyanidin and methylthioninium chloride, prescribed for 10 days. These compounds, along with nifuratel, are also successfully used in the form of a prophylactic reduced dose once per night for one to six months.http://kidneys.zaslavsky.com.ua/article/view/185117cystitisantibiotic resistancenifuratelсanephron hcombination of methylthioninium chloride and herbal extractscranberry extractcombination of purified lysates
spellingShingle D.D. Ivanov
Phytotherapy and treatment of cystitis: current trends
Počki
cystitis
antibiotic resistance
nifuratel
сanephron h
combination of methylthioninium chloride and herbal extracts
cranberry extract
combination of purified lysates
title Phytotherapy and treatment of cystitis: current trends
title_full Phytotherapy and treatment of cystitis: current trends
title_fullStr Phytotherapy and treatment of cystitis: current trends
title_full_unstemmed Phytotherapy and treatment of cystitis: current trends
title_short Phytotherapy and treatment of cystitis: current trends
title_sort phytotherapy and treatment of cystitis current trends
topic cystitis
antibiotic resistance
nifuratel
сanephron h
combination of methylthioninium chloride and herbal extracts
cranberry extract
combination of purified lysates
url http://kidneys.zaslavsky.com.ua/article/view/185117
work_keys_str_mv AT ddivanov phytotherapyandtreatmentofcystitiscurrenttrends