IS THERE ANY LINK BETWEEN A KIND OF THYROCYTE DYSFUNCTION, HYPOTHYROIDISM, AND INFLAMMATORY HEMATOLOGIC PARAMETERS IN THE CASES POSSESSING THE BENIGN THYROID NODULES? A 5-YEAR SINGLE-CENTRE EXPERIENCE
Objective: Microscopically, the thyroid gland is composed of spherical follicles and thyroid parenchyma includes two major cell types, the thyrocytes releasing thyroid hormones and C cells secreting mature calcitonin. Hypothyroidism has been known as being associated with the various abnormalities o...
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| Format: | Article |
| Language: | English |
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Association of medical doctors Sanamed Novi Pazar
2018-05-01
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| Series: | Sanamed |
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| Online Access: | http://www.sanamed.rs/OJS/index.php/Sanamed/article/view/211/112 |
| _version_ | 1797284518215811072 |
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| author | Sengul Demet Sengul Ilker |
| author_facet | Sengul Demet Sengul Ilker |
| author_sort | Sengul Demet |
| collection | DOAJ |
| description | Objective: Microscopically, the thyroid gland is composed of spherical follicles and thyroid parenchyma includes two major cell types, the thyrocytes releasing thyroid hormones and C cells secreting mature calcitonin. Hypothyroidism has been known as being associated with the various abnormalities of the coagulation system. In the present study, it had been purposed to inverstigate the relationship between inflammatory hematological parameters, RBC, Hb, Htc, RDW, WBC, neutrophil, lymhocyte, N/L, Plt, MPV, PCT, PDW and hypothyroid hormonal status in the cases possessing the benign thyroid nodules.
Material and Methods: A total of 313 cases, 202 with hypothyroidism, 111 with euthyroidism possesing the benign thyroid nodules, that was verified with the cytological evaluation after one-endocrine surgeon performed ultrasonography (US) guided fine needle aspiration (FNA) (US-g-FNA), at the Division of Endocrine Surgery, Department of General Surgery, Giresun University Faculty of Medicine, Giresun, Turkey, in conformity with the criteria, were enrolled into the study during the period, from April 2010 to April 2015. The documents that were used to follow consisted of laboratory tests of the cases including both the thyroid hormones, freeT3, FreeT4, and TSH, and the inflammatory hematological parameters were reviewed and scanned retrospectively. The upper limit of the normal Thyrotropin (TSH) reference range was determined as 4 mU/L in the present study.
Results: No statistically significant difference was found between the inflammatory hematological parameters, RBC, Hb, Htc, RDW, WBC, neutrophil, lymhocyte, N/L, Plt, MPV, PCT, PDW, and hypothyroidism (p>0.05).
Conclusion: Inflammatory hematological parameters may not be useful for estimating the hormonal status of the thyroid gland in the cases with the benign thyroid nodules verified with the cytological evaluation, TBSRTC. |
| first_indexed | 2024-03-07T17:49:02Z |
| format | Article |
| id | doaj.art-913fde213db14d2a8c32b67f36d6396a |
| institution | Directory Open Access Journal |
| issn | 1452-662X 2217-8171 |
| language | English |
| last_indexed | 2024-03-07T17:49:02Z |
| publishDate | 2018-05-01 |
| publisher | Association of medical doctors Sanamed Novi Pazar |
| record_format | Article |
| series | Sanamed |
| spelling | doaj.art-913fde213db14d2a8c32b67f36d6396a2024-03-02T14:21:09ZengAssociation of medical doctors Sanamed Novi PazarSanamed1452-662X2217-81712018-05-01131354010.24125/sanamed.v13i1.211IS THERE ANY LINK BETWEEN A KIND OF THYROCYTE DYSFUNCTION, HYPOTHYROIDISM, AND INFLAMMATORY HEMATOLOGIC PARAMETERS IN THE CASES POSSESSING THE BENIGN THYROID NODULES? A 5-YEAR SINGLE-CENTRE EXPERIENCESengul Demet0Sengul Ilker1Department of Pathology, Giresun University Faculty of Medicine, Giresun, TurkeyDivision of Endocrine Surgery, Department of General Surgery, Giresun University Faculty of Medicine, Giresun, TurkeyObjective: Microscopically, the thyroid gland is composed of spherical follicles and thyroid parenchyma includes two major cell types, the thyrocytes releasing thyroid hormones and C cells secreting mature calcitonin. Hypothyroidism has been known as being associated with the various abnormalities of the coagulation system. In the present study, it had been purposed to inverstigate the relationship between inflammatory hematological parameters, RBC, Hb, Htc, RDW, WBC, neutrophil, lymhocyte, N/L, Plt, MPV, PCT, PDW and hypothyroid hormonal status in the cases possessing the benign thyroid nodules. Material and Methods: A total of 313 cases, 202 with hypothyroidism, 111 with euthyroidism possesing the benign thyroid nodules, that was verified with the cytological evaluation after one-endocrine surgeon performed ultrasonography (US) guided fine needle aspiration (FNA) (US-g-FNA), at the Division of Endocrine Surgery, Department of General Surgery, Giresun University Faculty of Medicine, Giresun, Turkey, in conformity with the criteria, were enrolled into the study during the period, from April 2010 to April 2015. The documents that were used to follow consisted of laboratory tests of the cases including both the thyroid hormones, freeT3, FreeT4, and TSH, and the inflammatory hematological parameters were reviewed and scanned retrospectively. The upper limit of the normal Thyrotropin (TSH) reference range was determined as 4 mU/L in the present study. Results: No statistically significant difference was found between the inflammatory hematological parameters, RBC, Hb, Htc, RDW, WBC, neutrophil, lymhocyte, N/L, Plt, MPV, PCT, PDW, and hypothyroidism (p>0.05). Conclusion: Inflammatory hematological parameters may not be useful for estimating the hormonal status of the thyroid gland in the cases with the benign thyroid nodules verified with the cytological evaluation, TBSRTC.http://www.sanamed.rs/OJS/index.php/Sanamed/article/view/211/112Thyroid neoplasmsThyrocytesFine needle aspiration cytology (FNACCytologyThyrotropin (TSHHypothyroidismHematological parameters |
| spellingShingle | Sengul Demet Sengul Ilker IS THERE ANY LINK BETWEEN A KIND OF THYROCYTE DYSFUNCTION, HYPOTHYROIDISM, AND INFLAMMATORY HEMATOLOGIC PARAMETERS IN THE CASES POSSESSING THE BENIGN THYROID NODULES? A 5-YEAR SINGLE-CENTRE EXPERIENCE Sanamed Thyroid neoplasms Thyrocytes Fine needle aspiration cytology (FNAC Cytology Thyrotropin (TSH Hypothyroidism Hematological parameters |
| title | IS THERE ANY LINK BETWEEN A KIND OF THYROCYTE DYSFUNCTION, HYPOTHYROIDISM, AND INFLAMMATORY HEMATOLOGIC PARAMETERS IN THE CASES POSSESSING THE BENIGN THYROID NODULES? A 5-YEAR SINGLE-CENTRE EXPERIENCE |
| title_full | IS THERE ANY LINK BETWEEN A KIND OF THYROCYTE DYSFUNCTION, HYPOTHYROIDISM, AND INFLAMMATORY HEMATOLOGIC PARAMETERS IN THE CASES POSSESSING THE BENIGN THYROID NODULES? A 5-YEAR SINGLE-CENTRE EXPERIENCE |
| title_fullStr | IS THERE ANY LINK BETWEEN A KIND OF THYROCYTE DYSFUNCTION, HYPOTHYROIDISM, AND INFLAMMATORY HEMATOLOGIC PARAMETERS IN THE CASES POSSESSING THE BENIGN THYROID NODULES? A 5-YEAR SINGLE-CENTRE EXPERIENCE |
| title_full_unstemmed | IS THERE ANY LINK BETWEEN A KIND OF THYROCYTE DYSFUNCTION, HYPOTHYROIDISM, AND INFLAMMATORY HEMATOLOGIC PARAMETERS IN THE CASES POSSESSING THE BENIGN THYROID NODULES? A 5-YEAR SINGLE-CENTRE EXPERIENCE |
| title_short | IS THERE ANY LINK BETWEEN A KIND OF THYROCYTE DYSFUNCTION, HYPOTHYROIDISM, AND INFLAMMATORY HEMATOLOGIC PARAMETERS IN THE CASES POSSESSING THE BENIGN THYROID NODULES? A 5-YEAR SINGLE-CENTRE EXPERIENCE |
| title_sort | is there any link between a kind of thyrocyte dysfunction hypothyroidism and inflammatory hematologic parameters in the cases possessing the benign thyroid nodules a 5 year single centre experience |
| topic | Thyroid neoplasms Thyrocytes Fine needle aspiration cytology (FNAC Cytology Thyrotropin (TSH Hypothyroidism Hematological parameters |
| url | http://www.sanamed.rs/OJS/index.php/Sanamed/article/view/211/112 |
| work_keys_str_mv | AT senguldemet isthereanylinkbetweenakindofthyrocytedysfunctionhypothyroidismandinflammatoryhematologicparametersinthecasespossessingthebenignthyroidnodulesa5yearsinglecentreexperience AT sengulilker isthereanylinkbetweenakindofthyrocytedysfunctionhypothyroidismandinflammatoryhematologicparametersinthecasespossessingthebenignthyroidnodulesa5yearsinglecentreexperience |