Combined treatment for a large primary cardiac sarcoma: a case report
Abstract Background Undifferentiated pleomorphic sarcoma (UPS) as a primary cardiac tumor is rare, with extremely poor prognosis owing to high recurrence and invasion. We encountered a patient who presented with a primary cardiac tumor incarcerating the mitral valve and who was in a shock state. Cas...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2019-06-01
|
| Series: | Surgical Case Reports |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s40792-019-0658-x |
| _version_ | 1818214272973406208 |
|---|---|
| author | Shinji Akishima Akito Imai Yoshiharu Enomoto Osamu Shigeta |
| author_facet | Shinji Akishima Akito Imai Yoshiharu Enomoto Osamu Shigeta |
| author_sort | Shinji Akishima |
| collection | DOAJ |
| description | Abstract Background Undifferentiated pleomorphic sarcoma (UPS) as a primary cardiac tumor is rare, with extremely poor prognosis owing to high recurrence and invasion. We encountered a patient who presented with a primary cardiac tumor incarcerating the mitral valve and who was in a shock state. Case presentation A 41-year-old man was transported emergently to our hospital owing to acute respiratory distress and hemoptysis. He was diagnosed with acute left heart failure caused by a large mass in the left atrium (LA) that obstructed cardiac blood flow, as revealed by imaging study findings, and he underwent an emergency open-heart surgery for tumor resection. He was pathologically diagnosed with UPS invading the muscle layer of the LA. However, after receiving combined therapy for local recurrence and distant metastasis, including proton beam radiotherapy and chemotherapy with molecularly targeted drugs, he could return to work for 2 more years after surgery. Conclusion In this study, we reported the case of a patient who was in a state of shock state owing to the presence of UPS in the LA. The patient underwent an emergency surgery and received combined therapy. He survived for 2 more years after an initial diagnosis, without active local recurrence and distant metastasis. |
| first_indexed | 2024-12-12T06:17:33Z |
| format | Article |
| id | doaj.art-9144e49611ae44afaa71d69aa24f1457 |
| institution | Directory Open Access Journal |
| issn | 2198-7793 |
| language | English |
| last_indexed | 2024-12-12T06:17:33Z |
| publishDate | 2019-06-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj.art-9144e49611ae44afaa71d69aa24f14572022-12-22T00:34:59ZengSpringerOpenSurgical Case Reports2198-77932019-06-01511510.1186/s40792-019-0658-xCombined treatment for a large primary cardiac sarcoma: a case reportShinji Akishima0Akito Imai1Yoshiharu Enomoto2Osamu Shigeta3Department of Cardiovascular Surgery, Ibaraki Prefectural Central HospitalDepartment of Cardiovascular Surgery, Ibaraki Prefectural Central HospitalDepartment of Cardiovascular Surgery, Ibaraki Prefectural Central HospitalDepartment of Cardiovascular Surgery, Ibaraki Prefectural Central HospitalAbstract Background Undifferentiated pleomorphic sarcoma (UPS) as a primary cardiac tumor is rare, with extremely poor prognosis owing to high recurrence and invasion. We encountered a patient who presented with a primary cardiac tumor incarcerating the mitral valve and who was in a shock state. Case presentation A 41-year-old man was transported emergently to our hospital owing to acute respiratory distress and hemoptysis. He was diagnosed with acute left heart failure caused by a large mass in the left atrium (LA) that obstructed cardiac blood flow, as revealed by imaging study findings, and he underwent an emergency open-heart surgery for tumor resection. He was pathologically diagnosed with UPS invading the muscle layer of the LA. However, after receiving combined therapy for local recurrence and distant metastasis, including proton beam radiotherapy and chemotherapy with molecularly targeted drugs, he could return to work for 2 more years after surgery. Conclusion In this study, we reported the case of a patient who was in a state of shock state owing to the presence of UPS in the LA. The patient underwent an emergency surgery and received combined therapy. He survived for 2 more years after an initial diagnosis, without active local recurrence and distant metastasis.http://link.springer.com/article/10.1186/s40792-019-0658-xUndifferentiated pleomorphic sarcomaPrimary cardiac tumorAcute heart failureProton beam radiotherapyMolecular targeted drugsCombined therapy |
| spellingShingle | Shinji Akishima Akito Imai Yoshiharu Enomoto Osamu Shigeta Combined treatment for a large primary cardiac sarcoma: a case report Surgical Case Reports Undifferentiated pleomorphic sarcoma Primary cardiac tumor Acute heart failure Proton beam radiotherapy Molecular targeted drugs Combined therapy |
| title | Combined treatment for a large primary cardiac sarcoma: a case report |
| title_full | Combined treatment for a large primary cardiac sarcoma: a case report |
| title_fullStr | Combined treatment for a large primary cardiac sarcoma: a case report |
| title_full_unstemmed | Combined treatment for a large primary cardiac sarcoma: a case report |
| title_short | Combined treatment for a large primary cardiac sarcoma: a case report |
| title_sort | combined treatment for a large primary cardiac sarcoma a case report |
| topic | Undifferentiated pleomorphic sarcoma Primary cardiac tumor Acute heart failure Proton beam radiotherapy Molecular targeted drugs Combined therapy |
| url | http://link.springer.com/article/10.1186/s40792-019-0658-x |
| work_keys_str_mv | AT shinjiakishima combinedtreatmentforalargeprimarycardiacsarcomaacasereport AT akitoimai combinedtreatmentforalargeprimarycardiacsarcomaacasereport AT yoshiharuenomoto combinedtreatmentforalargeprimarycardiacsarcomaacasereport AT osamushigeta combinedtreatmentforalargeprimarycardiacsarcomaacasereport |