Probing the Residual Structure in Avian Prion Hexarepeats by CD, NMR and MD Techniques

Probing the Residual Structure in Avian Prion Hexarepeats by CD, NMR and MD Techniques

Many proteins perform essential biological functions by means of regions that lacking specific organized structure exist as an ensemble of interconverting transient conformers. The characterization of such regions, including the description of their structural propensities, number of conformations a...

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Bibliographic Details
Main Authors: Carla Isernia, Diego La Mendola, Gaetano Malgieri, Giuseppe Pappalardo, Roberto Fattorusso, Antonio Magrì, Luigi Russo, Maria Anna Campitiello, Luca Raiola
Format: Article
Language:English
Published: MDPI AG 2013-09-01
Series:Molecules
Subjects:
avian prion repeats
NMR
CD
conformational ensemble
polyproline II
Online Access:http://www.mdpi.com/1420-3049/18/9/11467

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