PVECs‐Derived Exosomal microRNAs Regulate PASMCs via FoxM1 Signaling in IUGR‐induced Pulmonary Hypertension

PVECs‐Derived Exosomal microRNAs Regulate PASMCs via FoxM1 Signaling in IUGR‐induced Pulmonary Hypertension

Background Intrauterine growth restriction (IUGR) is closely related to systemic or pulmonary hypertension (PH) in adulthood. Aberrant crosstalk between pulmonary vascular endothelial cells (PVECs) and pulmonary arterial smooth muscle cells (PASMCs) that is mediated by exosomes plays an essential ro...

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Bibliographic Details
Main Authors: Xiaofei Luo, Chengcheng Hang, Ziming Zhang, Kaixing Le, Yuhan Ying, Ying Lv, Lingling Yan, Yajie Huang, Lixia Ye, Xuefeng Xu, Ying Zhong, Lizhong Du
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
exosomal microRNAs
Forkhead box M1
intercellular communication
intrauterine growth restriction
pulmonary hypertension
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.122.027177

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