Biosynthesis of Novel Ascorbic Acid Esters and Their Encapsulation in Lignin Nanoparticles as Carriers and Stabilizing Systems
A dual-target strategy was designed for the application of lignin nanoparticles in the lipase mediated biosynthesis of novel 3-<i>O</i>-ethyl-L-ascorbyl-6-ferulate and 3-<i>O</i>-ethyl-L-ascorbyl-6-palmitate and in their successive solvent-shift encapsulation in order to impr...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-05-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/24/10/9044 |
| Summary: | A dual-target strategy was designed for the application of lignin nanoparticles in the lipase mediated biosynthesis of novel 3-<i>O</i>-ethyl-L-ascorbyl-6-ferulate and 3-<i>O</i>-ethyl-L-ascorbyl-6-palmitate and in their successive solvent-shift encapsulation in order to improve stability and antioxidant activity against temperature and pH-dependent degradation. The loaded lignin nanoparticles were fully characterized in terms of kinetic release, radical scavenging activity and stability under pH 3 and thermal stress (60 °C), showing improved antioxidant activity and high efficacy in the protection of ascorbic acid esters from degradation. |
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| ISSN: | 1661-6596 1422-0067 |