Epithelial JAM-A is fundamental for intestinal wound repair in vivo

Epithelial JAM-A is fundamental for intestinal wound repair in vivo

Junctional adhesion molecule-A (JAM-A) is expressed in several cell types, including epithelial and endothelial cells, as well as some leukocytes. In intestinal epithelial cells (IEC), JAM-A localizes to cell junctions and plays a role in regulating barrier function. In vitro studies with model cell...

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Bibliographic Details
Main Authors: Shuling Fan, Kevin Boerner, Chithra K. Muraleedharan, Asma Nusrat, Miguel Quiros, Charles A. Parkos
Format: Article
Language:English
Published: American Society for Clinical investigation 2022-09-01
Series:JCI Insight
Subjects:
Cell biology
Gastroenterology
Online Access:https://doi.org/10.1172/jci.insight.158934

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