Common Problems and Solutions in the Management of Resistant Gram-Negative Bacterial Infections: Expert Opinion on Clinical Practice
Antimicrobial resistance (AMR) in gram-negative bacteria is an escalating public health challenge nationally and globally. Since the beginning of the 2000s, antimicrobial resistance surveillance systems involving diverse stakeholders, including human healthcare, animal health, and agriculture, hav...
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| Format: | Article |
| Language: | English |
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Bilimsel Tip Yayinevi
2024-03-01
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| Series: | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
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| Online Access: | http://floradergisi.org/managete/fu_folder/2024-01/2024-29-01-1-24.pdf |
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| author | Şua SÜMER Özlem KURT AZAP Gökhan AYGÜN Halis AKALIN Murat AKOVA İftihar KÖKSAL |
| author_facet | Şua SÜMER Özlem KURT AZAP Gökhan AYGÜN Halis AKALIN Murat AKOVA İftihar KÖKSAL |
| author_sort | Şua SÜMER |
| collection | DOAJ |
| description | Antimicrobial resistance (AMR) in gram-negative bacteria is an escalating public health challenge nationally and globally. Since the
beginning of the 2000s, antimicrobial resistance surveillance systems involving diverse stakeholders, including human healthcare,
animal health, and agriculture, have been established worldwide under the leadership of the World Health Organization, merging local
AMR data and enabling the periodic release of reports on the AMR landscape, both regionally and internationally. As a result, crucial
components of an antimicrobial stewardship program have been identified, and implementation has been initiated at the national
level. However, considering the dynamic nature of AMR, it becomes apparent that existing guidelines and consensus reports, which offer
evidence-based, current literature insights and recommendations, may struggle to keep pace with the requirements of everyday clinical
practice. As this group of experts decided to prepare a guidance document tailored for Turkish clinicians, aimed at aiding in the diagnosis
and treatment of gram-negative bacterial infections with AMR in hospitalized patients, the Infectious Diseases Society of America (IDSA)
published the “2023 Guidance for the Treatment of AMD-Resistant Gram-Negative Infections” in July 2023. This indicates that the
developments in the field of AMR cannot be addressed by the guidelines in a timely manner. As Turkish Infectious Diseases and Clinical Microbiology specialists, we aspire for this article to serve as a valuable resource, offering guidance for healthcare practitioners across
various medical disciplines who treat patients afflicted by resistant gram-negative infections. |
| first_indexed | 2024-04-24T19:10:53Z |
| format | Article |
| id | doaj.art-91496dfc442d46639dc9728d827227c9 |
| institution | Directory Open Access Journal |
| issn | 1300-932X |
| language | English |
| last_indexed | 2024-04-24T19:10:53Z |
| publishDate | 2024-03-01 |
| publisher | Bilimsel Tip Yayinevi |
| record_format | Article |
| series | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
| spelling | doaj.art-91496dfc442d46639dc9728d827227c92024-03-26T10:20:31ZengBilimsel Tip YayineviFlora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi1300-932X2024-03-0129112410.5578/flora.2024011051Common Problems and Solutions in the Management of Resistant Gram-Negative Bacterial Infections: Expert Opinion on Clinical PracticeŞua SÜMER0https://orcid.org/0000-0003-3508-7516Özlem KURT AZAP1https://orcid.org/0000-0002-3171-8926Gökhan AYGÜN2https://orcid.org/0000-0001-6915-9843Halis AKALIN3https://orcid.org/0000-0001-7530-1279Murat AKOVA4https://orcid.org/0000-0002-6904-9473İftihar KÖKSAL5https://orcid.org/0000-0003-4892-8935Department of Infectious Diseases and Clinical Microbiology, Selçuk University Faculty of Medicine, Konya, TürkiyeDepartment of Infectious Diseases and Clinical Microbiology, Başkent University Faculty of Medicine, Ankara, TürkiyeDepartment of Infectious Diseases and Clinical Microbiology, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, TürkiyeDepartment of Infectious Diseases and Clinical Microbiology, Uludağ University Faculty of Medicine, Bursa, TürkiyeDepartment Infectious Diseases and Clinical Microbiology, Hacettepe University Faculty of Medicine, Ankara, TürkiyeDepartment Infectious Diseases and Clinical Microbiology, Acıbadem University Faculty of Medicine, İstanbul, TürkiyeAntimicrobial resistance (AMR) in gram-negative bacteria is an escalating public health challenge nationally and globally. Since the beginning of the 2000s, antimicrobial resistance surveillance systems involving diverse stakeholders, including human healthcare, animal health, and agriculture, have been established worldwide under the leadership of the World Health Organization, merging local AMR data and enabling the periodic release of reports on the AMR landscape, both regionally and internationally. As a result, crucial components of an antimicrobial stewardship program have been identified, and implementation has been initiated at the national level. However, considering the dynamic nature of AMR, it becomes apparent that existing guidelines and consensus reports, which offer evidence-based, current literature insights and recommendations, may struggle to keep pace with the requirements of everyday clinical practice. As this group of experts decided to prepare a guidance document tailored for Turkish clinicians, aimed at aiding in the diagnosis and treatment of gram-negative bacterial infections with AMR in hospitalized patients, the Infectious Diseases Society of America (IDSA) published the “2023 Guidance for the Treatment of AMD-Resistant Gram-Negative Infections” in July 2023. This indicates that the developments in the field of AMR cannot be addressed by the guidelines in a timely manner. As Turkish Infectious Diseases and Clinical Microbiology specialists, we aspire for this article to serve as a valuable resource, offering guidance for healthcare practitioners across various medical disciplines who treat patients afflicted by resistant gram-negative infections.http://floradergisi.org/managete/fu_folder/2024-01/2024-29-01-1-24.pdfgram-negative bacteriaantimicrobial drug resistancecarbapenem-resistancebeta-lactamase inhibitorsesbl |
| spellingShingle | Şua SÜMER Özlem KURT AZAP Gökhan AYGÜN Halis AKALIN Murat AKOVA İftihar KÖKSAL Common Problems and Solutions in the Management of Resistant Gram-Negative Bacterial Infections: Expert Opinion on Clinical Practice Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi gram-negative bacteria antimicrobial drug resistance carbapenem-resistance beta-lactamase inhibitors esbl |
| title | Common Problems and Solutions in the Management of Resistant Gram-Negative Bacterial Infections: Expert Opinion on Clinical Practice |
| title_full | Common Problems and Solutions in the Management of Resistant Gram-Negative Bacterial Infections: Expert Opinion on Clinical Practice |
| title_fullStr | Common Problems and Solutions in the Management of Resistant Gram-Negative Bacterial Infections: Expert Opinion on Clinical Practice |
| title_full_unstemmed | Common Problems and Solutions in the Management of Resistant Gram-Negative Bacterial Infections: Expert Opinion on Clinical Practice |
| title_short | Common Problems and Solutions in the Management of Resistant Gram-Negative Bacterial Infections: Expert Opinion on Clinical Practice |
| title_sort | common problems and solutions in the management of resistant gram negative bacterial infections expert opinion on clinical practice |
| topic | gram-negative bacteria antimicrobial drug resistance carbapenem-resistance beta-lactamase inhibitors esbl |
| url | http://floradergisi.org/managete/fu_folder/2024-01/2024-29-01-1-24.pdf |
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