Comparative effects of remifentanil and fentanyl on inflammatory stress response in mastectomy surgery with general anesthesia: A case series
Malignancy associated with chronic inflammation and stress response events by the surgical procedure. The use of an opioid such as remifentanil can decrease stress response that may be measured by leukocyte, neutrophil-to-lymphocyte ratio (NLR), platelet-to -lymphocyte ratio (PLR), mean platelet vol...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Bali Journal of Anesthesiology |
| Subjects: | |
| Online Access: | http://www.bjoaonline.com/article.asp?issn=2549-2276;year=2020;volume=4;issue=1;spage=18;epage=21;aulast=Agung |
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| author | Tjokorda Gde Agung Senapathi I Made Subagiartha I Gusti Agung Gede Utara Hartawan Adi Dharma Thius |
| author_facet | Tjokorda Gde Agung Senapathi I Made Subagiartha I Gusti Agung Gede Utara Hartawan Adi Dharma Thius |
| author_sort | Tjokorda Gde Agung Senapathi |
| collection | DOAJ |
| description | Malignancy associated with chronic inflammation and stress response events by the surgical procedure. The use of an opioid such as remifentanil can decrease stress response that may be measured by leukocyte, neutrophil-to-lymphocyte ratio (NLR), platelet-to -lymphocyte ratio (PLR), mean platelet volume, blood sugar, and C-reactive protein (CRP). This was a randomized, single-blind study, with a total sample of ten patients, and they were divided into two groups: 1.remifentanil group (0.1–0.3 mcg/kg body weight [BW]/min) and fentanyl group (intermittent 0.5–1 mcg/kg BW every 60 min). The patients' blood were collected two times before and 24 h after surgery. Inflammation markers such as total leukocyte value, NLR, PLR, and dan CRP were increased in two groups.Even PLR postoperative remains high in both group, but in remifentanil group was lower than fentanyl group. There were no differences between the two groups, but remifentanil was found better to suppress the postoperative PLR rather than in the fentanyl group. |
| first_indexed | 2024-12-16T17:28:32Z |
| format | Article |
| id | doaj.art-9149cbb5d285488ab01ac7ec99bdce08 |
| institution | Directory Open Access Journal |
| issn | 2549-2276 |
| language | English |
| last_indexed | 2024-12-16T17:28:32Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Bali Journal of Anesthesiology |
| spelling | doaj.art-9149cbb5d285488ab01ac7ec99bdce082022-12-21T22:22:59ZengWolters Kluwer Medknow PublicationsBali Journal of Anesthesiology2549-22762020-01-0141182110.4103/BJOA.BJOA_15_19Comparative effects of remifentanil and fentanyl on inflammatory stress response in mastectomy surgery with general anesthesia: A case seriesTjokorda Gde Agung SenapathiI Made SubagiarthaI Gusti Agung Gede Utara HartawanAdi Dharma ThiusMalignancy associated with chronic inflammation and stress response events by the surgical procedure. The use of an opioid such as remifentanil can decrease stress response that may be measured by leukocyte, neutrophil-to-lymphocyte ratio (NLR), platelet-to -lymphocyte ratio (PLR), mean platelet volume, blood sugar, and C-reactive protein (CRP). This was a randomized, single-blind study, with a total sample of ten patients, and they were divided into two groups: 1.remifentanil group (0.1–0.3 mcg/kg body weight [BW]/min) and fentanyl group (intermittent 0.5–1 mcg/kg BW every 60 min). The patients' blood were collected two times before and 24 h after surgery. Inflammation markers such as total leukocyte value, NLR, PLR, and dan CRP were increased in two groups.Even PLR postoperative remains high in both group, but in remifentanil group was lower than fentanyl group. There were no differences between the two groups, but remifentanil was found better to suppress the postoperative PLR rather than in the fentanyl group.http://www.bjoaonline.com/article.asp?issn=2549-2276;year=2020;volume=4;issue=1;spage=18;epage=21;aulast=Agungc-reactive proteinfentanylmean platelet volumeneutrophil-to-lymphocyte ratioplatelet-to-lymphocyte ratioremifentanil |
| spellingShingle | Tjokorda Gde Agung Senapathi I Made Subagiartha I Gusti Agung Gede Utara Hartawan Adi Dharma Thius Comparative effects of remifentanil and fentanyl on inflammatory stress response in mastectomy surgery with general anesthesia: A case series Bali Journal of Anesthesiology c-reactive protein fentanyl mean platelet volume neutrophil-to-lymphocyte ratio platelet-to-lymphocyte ratio remifentanil |
| title | Comparative effects of remifentanil and fentanyl on inflammatory stress response in mastectomy surgery with general anesthesia: A case series |
| title_full | Comparative effects of remifentanil and fentanyl on inflammatory stress response in mastectomy surgery with general anesthesia: A case series |
| title_fullStr | Comparative effects of remifentanil and fentanyl on inflammatory stress response in mastectomy surgery with general anesthesia: A case series |
| title_full_unstemmed | Comparative effects of remifentanil and fentanyl on inflammatory stress response in mastectomy surgery with general anesthesia: A case series |
| title_short | Comparative effects of remifentanil and fentanyl on inflammatory stress response in mastectomy surgery with general anesthesia: A case series |
| title_sort | comparative effects of remifentanil and fentanyl on inflammatory stress response in mastectomy surgery with general anesthesia a case series |
| topic | c-reactive protein fentanyl mean platelet volume neutrophil-to-lymphocyte ratio platelet-to-lymphocyte ratio remifentanil |
| url | http://www.bjoaonline.com/article.asp?issn=2549-2276;year=2020;volume=4;issue=1;spage=18;epage=21;aulast=Agung |
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