Dentinogenesis Imperfecta and Caries in Osteogenesis Imperfecta among Vietnamese Children
Osteogenesis imperfecta (OI) is a genetic disorder characterized by increased bone fragility and low bone mass, caused mainly by mutations in collagen type I encoding genes. The current study aimed to evaluate dentinogenesis imperfecta (DI), oral manifestations and caries status of OI children. Sixt...
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MDPI AG
2021-04-01
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| Series: | Dentistry Journal |
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| Online Access: | https://www.mdpi.com/2304-6767/9/5/49 |
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| author | Huong Thi Thu Nguyen Dung Chi Vu Duc Minh Nguyen Quang Dinh Dang Van Khanh Tran Hung Le Son Minh Tong |
| author_facet | Huong Thi Thu Nguyen Dung Chi Vu Duc Minh Nguyen Quang Dinh Dang Van Khanh Tran Hung Le Son Minh Tong |
| author_sort | Huong Thi Thu Nguyen |
| collection | DOAJ |
| description | Osteogenesis imperfecta (OI) is a genetic disorder characterized by increased bone fragility and low bone mass, caused mainly by mutations in collagen type I encoding genes. The current study aimed to evaluate dentinogenesis imperfecta (DI), oral manifestations and caries status of OI children. Sixty-eight children (41 males, 27 females) aged from 3 to 17 years old (mean 9 ± 4.13) participated in the study. Participants were classified into three OI type groups (I—2 cases, III—31 cases and IV—35 cases). Clinical examination and an orthopantomogram were used to obtain prevalences and associations of DI, caries status, malocclusion, crossbite, open bite, eruption, impaction and missing teeth with OI. The prevalence of DI among OI patients was 47.1%, more common in OI type III than type IV. The yellow-brown discoloration type was more vulnerable to attrition than the opalescent-grey one in the primary dentition. OI seemed not to have a high risk of caries; the prevalence of caries was 69.1%. A high incidence of malocclusion, crossbite and open bite was observed. In-depth oral information would provide valuable data for better dental management in OI patients. Parents and general doctors should pay more attention to dental care to prevent caries and premature tooth loss. |
| first_indexed | 2024-03-10T11:56:07Z |
| format | Article |
| id | doaj.art-914a387b60b44aa8b468814279579a32 |
| institution | Directory Open Access Journal |
| issn | 2304-6767 |
| language | English |
| last_indexed | 2024-03-10T11:56:07Z |
| publishDate | 2021-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Dentistry Journal |
| spelling | doaj.art-914a387b60b44aa8b468814279579a322023-11-21T17:20:51ZengMDPI AGDentistry Journal2304-67672021-04-01954910.3390/dj9050049Dentinogenesis Imperfecta and Caries in Osteogenesis Imperfecta among Vietnamese ChildrenHuong Thi Thu Nguyen0Dung Chi Vu1Duc Minh Nguyen2Quang Dinh Dang3Van Khanh Tran4Hung Le5Son Minh Tong6School of Odonto-Stomatology, Hanoi Medical University, Hanoi 100000, VietnamDepartment of Endocrinology, Metabolism and Genetics, Vietnam National Children’s Hospital, Hanoi 100000, VietnamSchool of Odonto-Stomatology, Hanoi Medical University, Hanoi 100000, VietnamFaculty of Dentistry, Hanoi University of Business and Technology, Hanoi 100000, VietnamCenter for Gene and Protein Research, Hanoi Medical University, Hanoi 100000, VietnamDong Da General Hospital, Hanoi 100000, VietnamSchool of Odonto-Stomatology, Hanoi Medical University, Hanoi 100000, VietnamOsteogenesis imperfecta (OI) is a genetic disorder characterized by increased bone fragility and low bone mass, caused mainly by mutations in collagen type I encoding genes. The current study aimed to evaluate dentinogenesis imperfecta (DI), oral manifestations and caries status of OI children. Sixty-eight children (41 males, 27 females) aged from 3 to 17 years old (mean 9 ± 4.13) participated in the study. Participants were classified into three OI type groups (I—2 cases, III—31 cases and IV—35 cases). Clinical examination and an orthopantomogram were used to obtain prevalences and associations of DI, caries status, malocclusion, crossbite, open bite, eruption, impaction and missing teeth with OI. The prevalence of DI among OI patients was 47.1%, more common in OI type III than type IV. The yellow-brown discoloration type was more vulnerable to attrition than the opalescent-grey one in the primary dentition. OI seemed not to have a high risk of caries; the prevalence of caries was 69.1%. A high incidence of malocclusion, crossbite and open bite was observed. In-depth oral information would provide valuable data for better dental management in OI patients. Parents and general doctors should pay more attention to dental care to prevent caries and premature tooth loss.https://www.mdpi.com/2304-6767/9/5/49cariesdentinogenesis imperfectaosteogenesis imperfecta |
| spellingShingle | Huong Thi Thu Nguyen Dung Chi Vu Duc Minh Nguyen Quang Dinh Dang Van Khanh Tran Hung Le Son Minh Tong Dentinogenesis Imperfecta and Caries in Osteogenesis Imperfecta among Vietnamese Children Dentistry Journal caries dentinogenesis imperfecta osteogenesis imperfecta |
| title | Dentinogenesis Imperfecta and Caries in Osteogenesis Imperfecta among Vietnamese Children |
| title_full | Dentinogenesis Imperfecta and Caries in Osteogenesis Imperfecta among Vietnamese Children |
| title_fullStr | Dentinogenesis Imperfecta and Caries in Osteogenesis Imperfecta among Vietnamese Children |
| title_full_unstemmed | Dentinogenesis Imperfecta and Caries in Osteogenesis Imperfecta among Vietnamese Children |
| title_short | Dentinogenesis Imperfecta and Caries in Osteogenesis Imperfecta among Vietnamese Children |
| title_sort | dentinogenesis imperfecta and caries in osteogenesis imperfecta among vietnamese children |
| topic | caries dentinogenesis imperfecta osteogenesis imperfecta |
| url | https://www.mdpi.com/2304-6767/9/5/49 |
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