Distinct cholangiocarcinoma cell migration in 2D monolayer and 3D spheroid culture based on galectin-3 expression and localization

Distinct cholangiocarcinoma cell migration in 2D monolayer and 3D spheroid culture based on galectin-3 expression and localization

IntroductionCholangiocarcinoma (CCA) is difficult to cure due to its ineffective treatment and advanced stage diagnosis. Thoroughly mechanistic understandings of CCA pathogenesis crucially help improving the treatment success rates. Using three-dimensional (3D) cell culture platform offers several a...

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Bibliographic Details
Main Authors: Siriwat Sukphokkit, Pichamon Kiatwuthinon, Supeecha Kumkate, Tavan Janvilisri
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
3D culture
spheroid
cholangiocarcinoma
galectin-3
cell migration
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.999158/full

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