An EWAS of dementia biomarkers and their associations with age, African ancestry, and PTSD

An EWAS of dementia biomarkers and their associations with age, African ancestry, and PTSD

Abstract Background Large-scale cohort and epidemiological studies suggest that PTSD confers risk for dementia in later life but the biological mechanisms underlying this association remain unknown. This study examined this question by assessing the influences of PTSD, APOE ε4 genotypes, DNA methyla...

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Bibliographic Details
Main Authors: Mark W. Miller, Erika J. Wolf, Xiang Zhao, Mark W. Logue, Sage E. Hawn
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Clinical Epigenetics
Subjects:
Aβ40
Aβ42
GFAP
NfL
pTau-181
PTSD
Online Access:https://doi.org/10.1186/s13148-024-01649-3

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