Age-Stratified T Cell Responses in Children Infected with Mycobacterium tuberculosis

Age-Stratified T Cell Responses in Children Infected with Mycobacterium tuberculosis

Tuberculosis (TB) in young children differs from adult TB in that the risk of rapid progression to active TB (aTB) is higher in children than in adults. The reasons for this increased risk are not fully understood. Early differentiation remains difficult between children at risk to develop aTB from...

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Bibliographic Details
Main Authors: Alexandra Dreesman, Véronique Corbière, Violette Dirix, Kaat Smits, Sara Debulpaep, Iris De Schutter, Myriam Libin, Mahavir Singh, Anne Malfroot, Camille Locht, Françoise Mascart
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Immunology
Subjects:
tuberculosis
children
interleukin-17
interferon-γ
tumor necrosis factor-α
heparin binding hemagglutinin
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01059/full

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