Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don’ts in Clinical Practice

In radiation oncology, little is known about possible difficulties in patients with Osteogenesis Imperfecta (OI). Because radiotherapy can cause various side-effects including bone, soft tissue and cardiovascular toxicities, we foresee that patients with OI may experience even more acute and late si...

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Bibliographic Details
Main Authors: Joyce E. Lodeweges, Fleur S. van Dijk, Joost J.C. Verhoeff
Format: Article
Language:English
Published: Karger Publishers 2019-04-01
Series:Case Reports in Oncology
Subjects:
Online Access:https://www.karger.com/Article/FullText/499903
Description
Summary:In radiation oncology, little is known about possible difficulties in patients with Osteogenesis Imperfecta (OI). Because radiotherapy can cause various side-effects including bone, soft tissue and cardiovascular toxicities, we foresee that patients with OI may experience even more acute and late side-effects due to pre-existing problems. We present two cases of radiotherapy in patients with OI, measured the effects of radiation on their bone mineral density and provide clinical recommendations for patient tailored radiotherapy strategies in patients with OI.
ISSN:1662-6575