Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don’ts in Clinical Practice

In radiation oncology, little is known about possible difficulties in patients with Osteogenesis Imperfecta (OI). Because radiotherapy can cause various side-effects including bone, soft tissue and cardiovascular toxicities, we foresee that patients with OI may experience even more acute and late si...

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Main Authors: Joyce E. Lodeweges, Fleur S. van Dijk, Joost J.C. Verhoeff
Format: Article
Language:English
Published: Karger Publishers 2019-04-01
Series:Case Reports in Oncology
Subjects:
Online Access:https://www.karger.com/Article/FullText/499903
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author Joyce E. Lodeweges
Fleur S. van Dijk
Joost J.C. Verhoeff
author_facet Joyce E. Lodeweges
Fleur S. van Dijk
Joost J.C. Verhoeff
author_sort Joyce E. Lodeweges
collection DOAJ
description In radiation oncology, little is known about possible difficulties in patients with Osteogenesis Imperfecta (OI). Because radiotherapy can cause various side-effects including bone, soft tissue and cardiovascular toxicities, we foresee that patients with OI may experience even more acute and late side-effects due to pre-existing problems. We present two cases of radiotherapy in patients with OI, measured the effects of radiation on their bone mineral density and provide clinical recommendations for patient tailored radiotherapy strategies in patients with OI.
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spelling doaj.art-9153479bcfc041b8b0eb34bacba8da112022-12-21T18:56:43ZengKarger PublishersCase Reports in Oncology1662-65752019-04-0112132233110.1159/000499903499903Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don’ts in Clinical PracticeJoyce E. LodewegesFleur S. van DijkJoost J.C. VerhoeffIn radiation oncology, little is known about possible difficulties in patients with Osteogenesis Imperfecta (OI). Because radiotherapy can cause various side-effects including bone, soft tissue and cardiovascular toxicities, we foresee that patients with OI may experience even more acute and late side-effects due to pre-existing problems. We present two cases of radiotherapy in patients with OI, measured the effects of radiation on their bone mineral density and provide clinical recommendations for patient tailored radiotherapy strategies in patients with OI.https://www.karger.com/Article/FullText/499903Osteogenesis imperfectaRadiotherapyToxicity
spellingShingle Joyce E. Lodeweges
Fleur S. van Dijk
Joost J.C. Verhoeff
Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don’ts in Clinical Practice
Case Reports in Oncology
Osteogenesis imperfecta
Radiotherapy
Toxicity
title Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don’ts in Clinical Practice
title_full Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don’ts in Clinical Practice
title_fullStr Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don’ts in Clinical Practice
title_full_unstemmed Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don’ts in Clinical Practice
title_short Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don’ts in Clinical Practice
title_sort radiotherapy late effects and osteogenesis imperfecta dos and don ts in clinical practice
topic Osteogenesis imperfecta
Radiotherapy
Toxicity
url https://www.karger.com/Article/FullText/499903
work_keys_str_mv AT joyceelodeweges radiotherapylateeffectsandosteogenesisimperfectadosanddontsinclinicalpractice
AT fleursvandijk radiotherapylateeffectsandosteogenesisimperfectadosanddontsinclinicalpractice
AT joostjcverhoeff radiotherapylateeffectsandosteogenesisimperfectadosanddontsinclinicalpractice