Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don’ts in Clinical Practice
In radiation oncology, little is known about possible difficulties in patients with Osteogenesis Imperfecta (OI). Because radiotherapy can cause various side-effects including bone, soft tissue and cardiovascular toxicities, we foresee that patients with OI may experience even more acute and late si...
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Format: | Article |
Language: | English |
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Karger Publishers
2019-04-01
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Series: | Case Reports in Oncology |
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Online Access: | https://www.karger.com/Article/FullText/499903 |
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author | Joyce E. Lodeweges Fleur S. van Dijk Joost J.C. Verhoeff |
author_facet | Joyce E. Lodeweges Fleur S. van Dijk Joost J.C. Verhoeff |
author_sort | Joyce E. Lodeweges |
collection | DOAJ |
description | In radiation oncology, little is known about possible difficulties in patients with Osteogenesis Imperfecta (OI). Because radiotherapy can cause various side-effects including bone, soft tissue and cardiovascular toxicities, we foresee that patients with OI may experience even more acute and late side-effects due to pre-existing problems. We present two cases of radiotherapy in patients with OI, measured the effects of radiation on their bone mineral density and provide clinical recommendations for patient tailored radiotherapy strategies in patients with OI. |
first_indexed | 2024-12-21T16:57:17Z |
format | Article |
id | doaj.art-9153479bcfc041b8b0eb34bacba8da11 |
institution | Directory Open Access Journal |
issn | 1662-6575 |
language | English |
last_indexed | 2024-12-21T16:57:17Z |
publishDate | 2019-04-01 |
publisher | Karger Publishers |
record_format | Article |
series | Case Reports in Oncology |
spelling | doaj.art-9153479bcfc041b8b0eb34bacba8da112022-12-21T18:56:43ZengKarger PublishersCase Reports in Oncology1662-65752019-04-0112132233110.1159/000499903499903Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don’ts in Clinical PracticeJoyce E. LodewegesFleur S. van DijkJoost J.C. VerhoeffIn radiation oncology, little is known about possible difficulties in patients with Osteogenesis Imperfecta (OI). Because radiotherapy can cause various side-effects including bone, soft tissue and cardiovascular toxicities, we foresee that patients with OI may experience even more acute and late side-effects due to pre-existing problems. We present two cases of radiotherapy in patients with OI, measured the effects of radiation on their bone mineral density and provide clinical recommendations for patient tailored radiotherapy strategies in patients with OI.https://www.karger.com/Article/FullText/499903Osteogenesis imperfectaRadiotherapyToxicity |
spellingShingle | Joyce E. Lodeweges Fleur S. van Dijk Joost J.C. Verhoeff Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don’ts in Clinical Practice Case Reports in Oncology Osteogenesis imperfecta Radiotherapy Toxicity |
title | Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don’ts in Clinical Practice |
title_full | Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don’ts in Clinical Practice |
title_fullStr | Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don’ts in Clinical Practice |
title_full_unstemmed | Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don’ts in Clinical Practice |
title_short | Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don’ts in Clinical Practice |
title_sort | radiotherapy late effects and osteogenesis imperfecta dos and don ts in clinical practice |
topic | Osteogenesis imperfecta Radiotherapy Toxicity |
url | https://www.karger.com/Article/FullText/499903 |
work_keys_str_mv | AT joyceelodeweges radiotherapylateeffectsandosteogenesisimperfectadosanddontsinclinicalpractice AT fleursvandijk radiotherapylateeffectsandosteogenesisimperfectadosanddontsinclinicalpractice AT joostjcverhoeff radiotherapylateeffectsandosteogenesisimperfectadosanddontsinclinicalpractice |