Iron Oxide Nanoparticles: Biosynthesis, Magnetic Behavior, Cytotoxic Effect
Abstract Iron oxide nanoparticles have attracted much attention because of their superparamagnetic properties and their potential applications in many fields such as magnetic storage devices, catalysis, sensors, superparamagnetic relaxometry (SPMR), and high‐sensitivity biomolecule magnetic resonanc...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley-VCH
2021-03-01
|
| Series: | ChemistryOpen |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/open.202000186 |
| _version_ | 1818725739380342784 |
|---|---|
| author | Dr. Abdolhossein Miri Dr. Hakimeh Najafzadeh Dr. Majid Darroudi Dr. Mohammad Javad Miri Dr. Mohammad Amin Jadidi Kouhbanani Mina Sarani |
| author_facet | Dr. Abdolhossein Miri Dr. Hakimeh Najafzadeh Dr. Majid Darroudi Dr. Mohammad Javad Miri Dr. Mohammad Amin Jadidi Kouhbanani Mina Sarani |
| author_sort | Dr. Abdolhossein Miri |
| collection | DOAJ |
| description | Abstract Iron oxide nanoparticles have attracted much attention because of their superparamagnetic properties and their potential applications in many fields such as magnetic storage devices, catalysis, sensors, superparamagnetic relaxometry (SPMR), and high‐sensitivity biomolecule magnetic resonance imaging (MRI) for medical diagnosis and therapeutics. In this study, iron oxide nanoparticles (Fe2O3 NPs) have been synthesized using a taranjabin (camelthorn or persian manna) aqueous solution. The synthesized Fe2O3 NPs were identified through powder X‐ray diffraction (PXRD), X‐ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FT‐IR), field energy scanning electron microscopy (FESEM), transmission electron microscopy (TEM), energy‐dispersive spectroscopy (EDX), vibrating‐sample magnetometer (VSM) and Raman technics. The results show that the nanoparticles have a hexagonal structure with 20 to 60 nm in size. The cytotoxic effect of the synthesized nanoparticles has been tested upon application against lung cancer cell (A549) lines. It was found that there is no cytotoxic activity at lower concentrations of 200 μg/mL. The ability of the synthesized nanoparticles for lead removal in wastewaters was tested. Results show that highest concentration of adsorbent (50 mg/L) has maximum removal efficiency (96.73 %). So, synthesized Fe2O3 NPs can be a good candidate to use as heavy metals cleaner from contaminated waters. |
| first_indexed | 2024-12-17T21:47:06Z |
| format | Article |
| id | doaj.art-9157c6c5e79e48e08e50829dc02d8362 |
| institution | Directory Open Access Journal |
| issn | 2191-1363 |
| language | English |
| last_indexed | 2024-12-17T21:47:06Z |
| publishDate | 2021-03-01 |
| publisher | Wiley-VCH |
| record_format | Article |
| series | ChemistryOpen |
| spelling | doaj.art-9157c6c5e79e48e08e50829dc02d83622022-12-21T21:31:26ZengWiley-VCHChemistryOpen2191-13632021-03-0110332733310.1002/open.202000186Iron Oxide Nanoparticles: Biosynthesis, Magnetic Behavior, Cytotoxic EffectDr. Abdolhossein Miri0Dr. Hakimeh Najafzadeh1Dr. Majid Darroudi2Dr. Mohammad Javad Miri3Dr. Mohammad Amin Jadidi Kouhbanani4Mina Sarani5Department of Pharmacognosy Faculty of Pharmacy Zabol University of Medical Sciences Zabol IranDepartment of Pharmacognosy Faculty of Pharmacy Zabol University of Medical Sciences Zabol IranNuclear Medicine Research Center Mashhad University of Medical Sciences Mashhad IranPediatric Gastroenterology and Hepatology Research Center Zabol University of Medical Sciences Zabol IranDepartment of Medical Nanotechnology, School of Advanced Technologies in Medicine Tehran University of Medical Sciences Tehran IranZabol Medicinal Plants Research Center Zabol University of Medical Sciences P.O. Box, 3333 669699 Zabol IranAbstract Iron oxide nanoparticles have attracted much attention because of their superparamagnetic properties and their potential applications in many fields such as magnetic storage devices, catalysis, sensors, superparamagnetic relaxometry (SPMR), and high‐sensitivity biomolecule magnetic resonance imaging (MRI) for medical diagnosis and therapeutics. In this study, iron oxide nanoparticles (Fe2O3 NPs) have been synthesized using a taranjabin (camelthorn or persian manna) aqueous solution. The synthesized Fe2O3 NPs were identified through powder X‐ray diffraction (PXRD), X‐ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FT‐IR), field energy scanning electron microscopy (FESEM), transmission electron microscopy (TEM), energy‐dispersive spectroscopy (EDX), vibrating‐sample magnetometer (VSM) and Raman technics. The results show that the nanoparticles have a hexagonal structure with 20 to 60 nm in size. The cytotoxic effect of the synthesized nanoparticles has been tested upon application against lung cancer cell (A549) lines. It was found that there is no cytotoxic activity at lower concentrations of 200 μg/mL. The ability of the synthesized nanoparticles for lead removal in wastewaters was tested. Results show that highest concentration of adsorbent (50 mg/L) has maximum removal efficiency (96.73 %). So, synthesized Fe2O3 NPs can be a good candidate to use as heavy metals cleaner from contaminated waters.https://doi.org/10.1002/open.202000186cytotoxic effectsiron oxide nanoparticleslead removalsuperparamagnetic effectsmanna derivatives |
| spellingShingle | Dr. Abdolhossein Miri Dr. Hakimeh Najafzadeh Dr. Majid Darroudi Dr. Mohammad Javad Miri Dr. Mohammad Amin Jadidi Kouhbanani Mina Sarani Iron Oxide Nanoparticles: Biosynthesis, Magnetic Behavior, Cytotoxic Effect ChemistryOpen cytotoxic effects iron oxide nanoparticles lead removal superparamagnetic effects manna derivatives |
| title | Iron Oxide Nanoparticles: Biosynthesis, Magnetic Behavior, Cytotoxic Effect |
| title_full | Iron Oxide Nanoparticles: Biosynthesis, Magnetic Behavior, Cytotoxic Effect |
| title_fullStr | Iron Oxide Nanoparticles: Biosynthesis, Magnetic Behavior, Cytotoxic Effect |
| title_full_unstemmed | Iron Oxide Nanoparticles: Biosynthesis, Magnetic Behavior, Cytotoxic Effect |
| title_short | Iron Oxide Nanoparticles: Biosynthesis, Magnetic Behavior, Cytotoxic Effect |
| title_sort | iron oxide nanoparticles biosynthesis magnetic behavior cytotoxic effect |
| topic | cytotoxic effects iron oxide nanoparticles lead removal superparamagnetic effects manna derivatives |
| url | https://doi.org/10.1002/open.202000186 |
| work_keys_str_mv | AT drabdolhosseinmiri ironoxidenanoparticlesbiosynthesismagneticbehaviorcytotoxiceffect AT drhakimehnajafzadeh ironoxidenanoparticlesbiosynthesismagneticbehaviorcytotoxiceffect AT drmajiddarroudi ironoxidenanoparticlesbiosynthesismagneticbehaviorcytotoxiceffect AT drmohammadjavadmiri ironoxidenanoparticlesbiosynthesismagneticbehaviorcytotoxiceffect AT drmohammadaminjadidikouhbanani ironoxidenanoparticlesbiosynthesismagneticbehaviorcytotoxiceffect AT minasarani ironoxidenanoparticlesbiosynthesismagneticbehaviorcytotoxiceffect |