Self-Association of Purified Reconstituted ER Luminal Spacer Climp63

Self-Association of Purified Reconstituted ER Luminal Spacer Climp63

Membranes of the endoplasmic reticulum (ER) are shaped into cisternal sheets and cylindrical tubules. How ER sheets are generated and maintained is not clear. ER membrane protein Climp63 is enriched in sheets and routinely used as a marker of this structure. The luminal domain (LD) of Climp63 is pre...

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Bibliographic Details
Main Authors: Jinghua Zhao, Junjie Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
endoplasmic reticulum
sheet biogenesis
membrane tethering
homotypic interactions
reconstitution
Climp63
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00500/full

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