Osteopontin in the host response to Leishmania amazonensis

Osteopontin in the host response to Leishmania amazonensis

Abstract Background Leishmania (L.) spp are intracellular eukaryotic parasites responsible for cutaneous or visceral leishmaniasis, replicating predominantly in macrophages (MF). In C57BL/6 mice virulence with L. amazonensis has been associated with inhibition of Th1 immune responses and an uncontro...

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Bibliographic Details
Main Authors: Emilie Giraud, Eline Rouault, Laurence Fiette, Jean-Hervé Colle, Despoina Smirlis, Evie Melanitou
Format: Article
Language:English
Published: BMC 2019-02-01
Series:BMC Microbiology
Subjects:
Osteopontin
Macrophage
Inflammation
Inflammasome
Pyroptosis
Parasites
Online Access:http://link.springer.com/article/10.1186/s12866-019-1404-z

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