The amino‐terminal domain of Mycobacterium tuberculosis ClpB protein plays a crucial role in its substrate disaggregation activity

Mycobacterium tuberculosis (Mtb) is known to persist in extremely hostile environments within host macrophages. The ability to withstand such proteotoxic stress comes from its highly conserved molecular chaperone machinery. ClpB, a unique member of the AAA+ family of chaperones, is responsible for r...

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Bibliographic Details
Main Authors: Prajna Tripathi, Priyanka Parijat, Virendra Kumar Patel, Janendra K. Batra
Format: Article
Language:English
Published: Wiley 2018-10-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12509

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