CMPK2 is a host restriction factor that inhibits infection of multiple coronaviruses in a cell-intrinsic manner.
Coronaviruses (CoVs) comprise a group of important human and animal pathogens. Despite extensive research in the past 3 years, the host innate immune defense mechanisms against CoVs remain incompletely understood, limiting the development of effective antivirals and non-antibody-based therapeutics....
Main Authors: | Mingjun Zhu, Jiahuang Lv, Wei Wang, Rongli Guo, Chunyan Zhong, Avan Antia, Qiru Zeng, Jizong Li, Qingtao Liu, Jinzhu Zhou, Xuejiao Zhu, Baochao Fan, Siyuan Ding, Bin Li |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2023-03-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.3002039 |
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