Impact of Polymer Membrane Properties on the Removal of Pharmaceuticals
The influence of various factors on the removal efficiency of selected pharmaceuticals by membrane filtration was investigated. Several commercial polymer membranes were used for nanofiltration (NF) from various manufacturers. The studies were conducted for ibuprofen (IBF), amoxicillin (AMX), diclof...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-01-01
|
| Series: | Membranes |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0375/12/2/150 |
| _version_ | 1827654021919277056 |
|---|---|
| author | Renata Żyłła Magdalena Foszpańczyk Irena Kamińska Marcin Kudzin Jacek Balcerzak Stanisław Ledakowicz |
| author_facet | Renata Żyłła Magdalena Foszpańczyk Irena Kamińska Marcin Kudzin Jacek Balcerzak Stanisław Ledakowicz |
| author_sort | Renata Żyłła |
| collection | DOAJ |
| description | The influence of various factors on the removal efficiency of selected pharmaceuticals by membrane filtration was investigated. Several commercial polymer membranes were used for nanofiltration (NF) from various manufacturers. The studies were conducted for ibuprofen (IBF), amoxicillin (AMX), diclofenac (DCF), tetracycline (TRC), salicylic acid (SA) and acetylsalicylic acid (ASA). The influence of the structure and properties of the tested compounds on the retention coefficient and filtration rate was investigated. The influence of pH on the filtration parameters was also checked. The properties of selected membranes influencing the retention of pharmaceuticals and filtrate flux were analysed. An extensive analysis of the retention coefficients dependence on the contact angle and surface free energy was performed. It was found that there is a correlation between the hydrophilicity of the membrane and the effectiveness and efficiency of the membrane. As the contact angle of membrane increased, the flow rate of the filtrate stream increased, while the retention coefficient decreased. The studies showed that the best separation efficiency was achieved for compounds with a molecular weight (MW) greater than 300 g/mol. During the filtration of pharmaceuticals with MW ranging from 300 to 450 g/mol, the type of membrane used practically did not affect the filtration efficiency and a high degree of retention was achieved. In the case of low MW molecules (SA and ASA), a significant decrease in the separation efficiency during the process was noted. |
| first_indexed | 2024-03-09T21:28:42Z |
| format | Article |
| id | doaj.art-915e1950419e434ca22e9e845fef4d0a |
| institution | Directory Open Access Journal |
| issn | 2077-0375 |
| language | English |
| last_indexed | 2024-03-09T21:28:42Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Membranes |
| spelling | doaj.art-915e1950419e434ca22e9e845fef4d0a2023-11-23T21:02:36ZengMDPI AGMembranes2077-03752022-01-0112215010.3390/membranes12020150Impact of Polymer Membrane Properties on the Removal of PharmaceuticalsRenata Żyłła0Magdalena Foszpańczyk1Irena Kamińska2Marcin Kudzin3Jacek Balcerzak4Stanisław Ledakowicz5Łukasiewicz Research Network-Textile Research Institute, ul. Brzezińska 5/15, 92-103 Łódź, PolandŁukasiewicz Research Network-Textile Research Institute, ul. Brzezińska 5/15, 92-103 Łódź, PolandŁukasiewicz Research Network-Textile Research Institute, ul. Brzezińska 5/15, 92-103 Łódź, PolandŁukasiewicz Research Network-Textile Research Institute, ul. Brzezińska 5/15, 92-103 Łódź, PolandDepartment of Molecular Engineering, Faculty of Process and Environmental Engineering, Lodz University of Technology, Wólczańska 213, 93-005 Łódź, PolandDepartment of Bioprocess Engineering, Faculty of Process and Environmental Engineering, Lodz University of Technology, ul. Wólczańska 213, 93-005 Łódź, PolandThe influence of various factors on the removal efficiency of selected pharmaceuticals by membrane filtration was investigated. Several commercial polymer membranes were used for nanofiltration (NF) from various manufacturers. The studies were conducted for ibuprofen (IBF), amoxicillin (AMX), diclofenac (DCF), tetracycline (TRC), salicylic acid (SA) and acetylsalicylic acid (ASA). The influence of the structure and properties of the tested compounds on the retention coefficient and filtration rate was investigated. The influence of pH on the filtration parameters was also checked. The properties of selected membranes influencing the retention of pharmaceuticals and filtrate flux were analysed. An extensive analysis of the retention coefficients dependence on the contact angle and surface free energy was performed. It was found that there is a correlation between the hydrophilicity of the membrane and the effectiveness and efficiency of the membrane. As the contact angle of membrane increased, the flow rate of the filtrate stream increased, while the retention coefficient decreased. The studies showed that the best separation efficiency was achieved for compounds with a molecular weight (MW) greater than 300 g/mol. During the filtration of pharmaceuticals with MW ranging from 300 to 450 g/mol, the type of membrane used practically did not affect the filtration efficiency and a high degree of retention was achieved. In the case of low MW molecules (SA and ASA), a significant decrease in the separation efficiency during the process was noted.https://www.mdpi.com/2077-0375/12/2/150nanofiltrationpharmaceuticalshazardous materialsmembrane filtrationamoxicillindiclofenac |
| spellingShingle | Renata Żyłła Magdalena Foszpańczyk Irena Kamińska Marcin Kudzin Jacek Balcerzak Stanisław Ledakowicz Impact of Polymer Membrane Properties on the Removal of Pharmaceuticals Membranes nanofiltration pharmaceuticals hazardous materials membrane filtration amoxicillin diclofenac |
| title | Impact of Polymer Membrane Properties on the Removal of Pharmaceuticals |
| title_full | Impact of Polymer Membrane Properties on the Removal of Pharmaceuticals |
| title_fullStr | Impact of Polymer Membrane Properties on the Removal of Pharmaceuticals |
| title_full_unstemmed | Impact of Polymer Membrane Properties on the Removal of Pharmaceuticals |
| title_short | Impact of Polymer Membrane Properties on the Removal of Pharmaceuticals |
| title_sort | impact of polymer membrane properties on the removal of pharmaceuticals |
| topic | nanofiltration pharmaceuticals hazardous materials membrane filtration amoxicillin diclofenac |
| url | https://www.mdpi.com/2077-0375/12/2/150 |
| work_keys_str_mv | AT renatazyłła impactofpolymermembranepropertiesontheremovalofpharmaceuticals AT magdalenafoszpanczyk impactofpolymermembranepropertiesontheremovalofpharmaceuticals AT irenakaminska impactofpolymermembranepropertiesontheremovalofpharmaceuticals AT marcinkudzin impactofpolymermembranepropertiesontheremovalofpharmaceuticals AT jacekbalcerzak impactofpolymermembranepropertiesontheremovalofpharmaceuticals AT stanisławledakowicz impactofpolymermembranepropertiesontheremovalofpharmaceuticals |