Effect of isometric exercise on blood pressure in prehypertensive and hypertensive individuals: protocol for a systematic review and meta-analysis of randomized controlled trials
Abstract Background Systemic arterial hypertension (HTN) is the leading risk factor of cardiovascular disease death. Lifestyle changes are key for the prevention and management of HTN. Regular aerobic exercise training is recommended as part of the management of HTN, and dynamic resistance exercise...
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| Format: | Article |
| Language: | English |
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BMC
2022-05-01
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| Series: | Systematic Reviews |
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| Online Access: | https://doi.org/10.1186/s13643-022-01974-9 |
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| author | Patrícia Caetano de Oliveira Alexandre M. Lehnen Gustavo Waclawovsky |
| author_facet | Patrícia Caetano de Oliveira Alexandre M. Lehnen Gustavo Waclawovsky |
| author_sort | Patrícia Caetano de Oliveira |
| collection | DOAJ |
| description | Abstract Background Systemic arterial hypertension (HTN) is the leading risk factor of cardiovascular disease death. Lifestyle changes are key for the prevention and management of HTN. Regular aerobic exercise training is recommended as part of the management of HTN, and dynamic resistance exercise should be prescribed as an adjuvant to aerobic training. Recent evidence points to the potential benefits of isometric resistance training in reducing blood pressure (BP). Yet, the hypotensive effect of isometric exercise in prehypertensive and hypertensive individuals is not fully understood. Thus, we will examine the effect of isometric exercise in prehypertensive and hypertensive individuals through a systematic review and meta-analysis. Methods Our systematic review study will include randomized controlled trials (RCTs) selected from the electronic databases MEDLINE (PubMed), Cochrane, LILACS, EMBASE, Web of Science, and PEDro published in English, Spanish, and Portuguese languages. We will follow the PRISMA-P (Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols) and PICOS framework. Our search will involve studies with both male and female participants aged 18 years or more diagnosed with prehypertension or HTN performing one session of isometric exercise (acute effect) or isometric exercise training (chronic effect) compared to a control group (no exercise). We will use the Cochrane Risk of Bias 2 (RoB 2) tool to evaluate the quality of the studies and RStudio software (v1.3.959 for Windows) for statistical analyses. Discussion A meta-analysis of a homogeneous sample of prehypertensive and hypertensive individuals involving isometric handgrip exercise alone can further support previous findings and improve our understanding and recommendations for the management of these populations. Systematic review registration PROSPERO CRD42020213081. |
| first_indexed | 2024-12-12T13:00:59Z |
| format | Article |
| id | doaj.art-91653ee8ccbb41e3add8535a4e7eff4f |
| institution | Directory Open Access Journal |
| issn | 2046-4053 |
| language | English |
| last_indexed | 2024-12-12T13:00:59Z |
| publishDate | 2022-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Systematic Reviews |
| spelling | doaj.art-91653ee8ccbb41e3add8535a4e7eff4f2022-12-22T00:23:48ZengBMCSystematic Reviews2046-40532022-05-011111910.1186/s13643-022-01974-9Effect of isometric exercise on blood pressure in prehypertensive and hypertensive individuals: protocol for a systematic review and meta-analysis of randomized controlled trialsPatrícia Caetano de Oliveira0Alexandre M. Lehnen1Gustavo Waclawovsky2Instituto de Cardiologia do Rio Grande do Sul/Fundação Universitária de CardiologiaInstituto de Cardiologia do Rio Grande do Sul/Fundação Universitária de CardiologiaInstituto de Cardiologia do Rio Grande do Sul/Fundação Universitária de CardiologiaAbstract Background Systemic arterial hypertension (HTN) is the leading risk factor of cardiovascular disease death. Lifestyle changes are key for the prevention and management of HTN. Regular aerobic exercise training is recommended as part of the management of HTN, and dynamic resistance exercise should be prescribed as an adjuvant to aerobic training. Recent evidence points to the potential benefits of isometric resistance training in reducing blood pressure (BP). Yet, the hypotensive effect of isometric exercise in prehypertensive and hypertensive individuals is not fully understood. Thus, we will examine the effect of isometric exercise in prehypertensive and hypertensive individuals through a systematic review and meta-analysis. Methods Our systematic review study will include randomized controlled trials (RCTs) selected from the electronic databases MEDLINE (PubMed), Cochrane, LILACS, EMBASE, Web of Science, and PEDro published in English, Spanish, and Portuguese languages. We will follow the PRISMA-P (Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols) and PICOS framework. Our search will involve studies with both male and female participants aged 18 years or more diagnosed with prehypertension or HTN performing one session of isometric exercise (acute effect) or isometric exercise training (chronic effect) compared to a control group (no exercise). We will use the Cochrane Risk of Bias 2 (RoB 2) tool to evaluate the quality of the studies and RStudio software (v1.3.959 for Windows) for statistical analyses. Discussion A meta-analysis of a homogeneous sample of prehypertensive and hypertensive individuals involving isometric handgrip exercise alone can further support previous findings and improve our understanding and recommendations for the management of these populations. Systematic review registration PROSPERO CRD42020213081.https://doi.org/10.1186/s13643-022-01974-9PrehypertensionHypertensionBlood pressureIsometric exercise |
| spellingShingle | Patrícia Caetano de Oliveira Alexandre M. Lehnen Gustavo Waclawovsky Effect of isometric exercise on blood pressure in prehypertensive and hypertensive individuals: protocol for a systematic review and meta-analysis of randomized controlled trials Systematic Reviews Prehypertension Hypertension Blood pressure Isometric exercise |
| title | Effect of isometric exercise on blood pressure in prehypertensive and hypertensive individuals: protocol for a systematic review and meta-analysis of randomized controlled trials |
| title_full | Effect of isometric exercise on blood pressure in prehypertensive and hypertensive individuals: protocol for a systematic review and meta-analysis of randomized controlled trials |
| title_fullStr | Effect of isometric exercise on blood pressure in prehypertensive and hypertensive individuals: protocol for a systematic review and meta-analysis of randomized controlled trials |
| title_full_unstemmed | Effect of isometric exercise on blood pressure in prehypertensive and hypertensive individuals: protocol for a systematic review and meta-analysis of randomized controlled trials |
| title_short | Effect of isometric exercise on blood pressure in prehypertensive and hypertensive individuals: protocol for a systematic review and meta-analysis of randomized controlled trials |
| title_sort | effect of isometric exercise on blood pressure in prehypertensive and hypertensive individuals protocol for a systematic review and meta analysis of randomized controlled trials |
| topic | Prehypertension Hypertension Blood pressure Isometric exercise |
| url | https://doi.org/10.1186/s13643-022-01974-9 |
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