Novel Highly Divergent SARS-CoV-2 Lineage With the Spike Substitutions L249S and E484K

Novel Highly Divergent SARS-CoV-2 Lineage With the Spike Substitutions L249S and E484K

COVID-19 pandemics has led to genetic diversification of SARS-CoV-2 and the appearance of variants with potential impact in transmissibility and viral escape from acquired immunity. We report a new and highly divergent lineage containing 21 distinctive mutations (10 non-synonymous, eight synonymous,...

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Bibliographic Details
Main Authors: Katherine Laiton-Donato, Jose A. Usme-Ciro, Carlos Franco-Muñoz, Diego A. Álvarez-Díaz, Hector Alejandro Ruiz-Moreno, Jhonnatan Reales-González, Diego Andrés Prada, Sheryll Corchuelo, Maria T. Herrera-Sepúlveda, Julian Naizaque, Gerardo Santamaría, Magdalena Wiesner, Diana Marcela Walteros, Martha Lucia Ospina Martínez, Marcela Mercado-Reyes
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Medicine
Subjects:
SARS-CoV-2
lineage
COVID-19
spike
variant of interest
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.697605/full

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