Immunoinformatics Evaluation of a Fusion Protein Composed of Leishmania infantum LiHyV and Phlebotomus kandelakii Apyrase as a Vaccine Candidate against Visceral Leishmaniasis

Immunoinformatics Evaluation of a Fusion Protein Composed of Leishmania infantum LiHyV and Phlebotomus kandelakii Apyrase as a Vaccine Candidate against Visceral Leishmaniasis

Background: Visceral leishmaniasis (VL) is a lethal parasitic disease, transmitted by sand fly vectors. Immunomodulatory properties of sand fly saliva proteins and their protective effects against Leishmania infection in pre-exposed animals suggest that a combination of an antigenic salivary protei...

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Bibliographic Details
Main Authors: Shima Fayaz, Fariborz Bahrami, Pezhman Fard-Esfahani, Parviz Parvizi, Golnaz Bahramali, Soheila Ajdary
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2022-05-01
Series:Iranian Journal of Parasitology
Subjects:
Immunoinformatics
Leishmania infantum
Phlebotomus kandelakii
Apyrase
Vaccine
Online Access:https://ijpa.tums.ac.ir/index.php/ijpa/article/view/3466

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