Serotonin syndrome in a postoperative patient

Depression is common in patients with ischemic heart disease. According to mental health surveys, approximately one-fifth of the patients with angiographic evidence of coronary artery disease have major depression. [1] It is well-recognized that stigma associated with mental disorders leads to indiv...

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Main Authors: Minati Choudhury, Milind P Hote, Yashwant Verma
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-01-01
Series:Journal of Anaesthesiology Clinical Pharmacology
Subjects:
Online Access:http://www.joacp.org/article.asp?issn=0970-9185;year=2011;volume=27;issue=2;spage=233;epage=235;aulast=Choudhury
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author Minati Choudhury
Milind P Hote
Yashwant Verma
author_facet Minati Choudhury
Milind P Hote
Yashwant Verma
author_sort Minati Choudhury
collection DOAJ
description Depression is common in patients with ischemic heart disease. According to mental health surveys, approximately one-fifth of the patients with angiographic evidence of coronary artery disease have major depression. [1] It is well-recognized that stigma associated with mental disorders leads to individuals avoiding treatment or concealing treatment for them. We report a case of serotonin syndrome that occurred during postoperative period in a patient who underwent coronary artery bypass grafting. The patient was receiving 60 mg/day fluoxetine for the last 4 years, which she and her attendants concealed during the preoperative evaluation. To our knowledge this is the first case of serotonin syndrome, reported in biomedical literature, in a postoperative patient. We suggest that history taking should also focus on antidepressant drug intake by patients. If serotonin syndrome occurs in such patients aggressive and timely management can help avert mortality.
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spelling doaj.art-9168384832ca4a2b9b6798e62caff3832022-12-21T19:20:46ZengWolters Kluwer Medknow PublicationsJournal of Anaesthesiology Clinical Pharmacology0970-91852011-01-0127223323510.4103/0970-9185.81825Serotonin syndrome in a postoperative patientMinati ChoudhuryMilind P HoteYashwant VermaDepression is common in patients with ischemic heart disease. According to mental health surveys, approximately one-fifth of the patients with angiographic evidence of coronary artery disease have major depression. [1] It is well-recognized that stigma associated with mental disorders leads to individuals avoiding treatment or concealing treatment for them. We report a case of serotonin syndrome that occurred during postoperative period in a patient who underwent coronary artery bypass grafting. The patient was receiving 60 mg/day fluoxetine for the last 4 years, which she and her attendants concealed during the preoperative evaluation. To our knowledge this is the first case of serotonin syndrome, reported in biomedical literature, in a postoperative patient. We suggest that history taking should also focus on antidepressant drug intake by patients. If serotonin syndrome occurs in such patients aggressive and timely management can help avert mortality.http://www.joacp.org/article.asp?issn=0970-9185;year=2011;volume=27;issue=2;spage=233;epage=235;aulast=ChoudhuryCardiac surgeryfluoxetineserotonin syndrome
spellingShingle Minati Choudhury
Milind P Hote
Yashwant Verma
Serotonin syndrome in a postoperative patient
Journal of Anaesthesiology Clinical Pharmacology
Cardiac surgery
fluoxetine
serotonin syndrome
title Serotonin syndrome in a postoperative patient
title_full Serotonin syndrome in a postoperative patient
title_fullStr Serotonin syndrome in a postoperative patient
title_full_unstemmed Serotonin syndrome in a postoperative patient
title_short Serotonin syndrome in a postoperative patient
title_sort serotonin syndrome in a postoperative patient
topic Cardiac surgery
fluoxetine
serotonin syndrome
url http://www.joacp.org/article.asp?issn=0970-9185;year=2011;volume=27;issue=2;spage=233;epage=235;aulast=Choudhury
work_keys_str_mv AT minatichoudhury serotoninsyndromeinapostoperativepatient
AT milindphote serotoninsyndromeinapostoperativepatient
AT yashwantverma serotoninsyndromeinapostoperativepatient