Mechanism of increased risk of insulin resistance in aging skeletal muscle
Abstract As age increases, the risk of developing type 2 diabetes increases, which is associated with senile skeletal muscle dysfunction. During skeletal muscle aging, mitochondrial dysfunction, intramyocellular lipid accumulation, increased inflammation, oxidative stress, modified activity of insul...
Main Authors: | Jian Shou, Pei-Jie Chen, Wei-Hua Xiao |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-02-01
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Series: | Diabetology & Metabolic Syndrome |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13098-020-0523-x |
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