A systematic review of ECG findings in patients with COVID-19
Introduction: Since the epidemic of COVID-19 attracted the attention, reports were surrounding electrocardiographic changes in the infected individuals. We aimed at pinpointing different observed ECG findings and discussing their clinical significance. Methods: We conducted a systematic search in Pu...
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Format: | Article |
Language: | English |
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Elsevier
2020-11-01
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Series: | Indian Heart Journal |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S001948322030273X |
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author | Esmaeil Mehraeen Seyed Ahmad Seyed Alinaghi Ali Nowroozi Omid Dadras Sanam Alilou Parnian Shobeiri Farzane Behnezhad Amirali Karimi |
author_facet | Esmaeil Mehraeen Seyed Ahmad Seyed Alinaghi Ali Nowroozi Omid Dadras Sanam Alilou Parnian Shobeiri Farzane Behnezhad Amirali Karimi |
author_sort | Esmaeil Mehraeen |
collection | DOAJ |
description | Introduction: Since the epidemic of COVID-19 attracted the attention, reports were surrounding electrocardiographic changes in the infected individuals. We aimed at pinpointing different observed ECG findings and discussing their clinical significance. Methods: We conducted a systematic search in PubMed, Embase, and Scopus databases. We included eligible original papers, reports, letters to the editors, and case reports published from December 2019 to May 10, 2020. Results: The team identified 20 articles related to this topic. We divided them into articles discussing drug-induced and non-drug-induced changes. Studies reported an increased risk of QTc interval prolongations influenced by different therapies based on chloroquine, hydroxychloroquine, and azithromycin. Although these medications increased risks of severe QTc prolongations, they induced no arrhythmia-related deaths. In the non-drug-induced group, ST-T abnormalities, notably ST elevation, accounted for the most observed ECG finding in the patients with COVID-19, but their relation with myocardial injuries was under dispute. Conclusion: This systematic review suggests that identifying ECG patterns that might be related to COVID-19 is vital. Provided that physicians do not recognize these patterns, they might erroneously risk the lives of their patients. Furthermore, important drug-induced ECG changes provide awareness to the health-care workers on the risks of possible therapies. |
first_indexed | 2024-12-24T01:33:11Z |
format | Article |
id | doaj.art-9172734886c3492b88a05bbabf43ed5b |
institution | Directory Open Access Journal |
issn | 0019-4832 |
language | English |
last_indexed | 2024-12-24T01:33:11Z |
publishDate | 2020-11-01 |
publisher | Elsevier |
record_format | Article |
series | Indian Heart Journal |
spelling | doaj.art-9172734886c3492b88a05bbabf43ed5b2022-12-21T17:22:17ZengElsevierIndian Heart Journal0019-48322020-11-01726500507A systematic review of ECG findings in patients with COVID-19Esmaeil Mehraeen0Seyed Ahmad Seyed Alinaghi1Ali Nowroozi2Omid Dadras3Sanam Alilou4Parnian Shobeiri5Farzane Behnezhad6Amirali Karimi7Department of Health Information Technology, Khalkhal University of Medical Sciences, Khalkhal, IranIranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High Risk Behaviors, Tehran University of Medical Sciences, Tehran, IranSchool of Medicine, Tehran University of Medical Sciences, Tehran, IranDepartment of Health Informatics, Graduate School of Medicine, Kyoto University, Kyoto, JapanSchool of Medicine, Tehran University of Medical Sciences, Tehran, IranSchool of Medicine, Tehran University of Medical Sciences, Tehran, IranDepartment of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, IranSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Corresponding author.Introduction: Since the epidemic of COVID-19 attracted the attention, reports were surrounding electrocardiographic changes in the infected individuals. We aimed at pinpointing different observed ECG findings and discussing their clinical significance. Methods: We conducted a systematic search in PubMed, Embase, and Scopus databases. We included eligible original papers, reports, letters to the editors, and case reports published from December 2019 to May 10, 2020. Results: The team identified 20 articles related to this topic. We divided them into articles discussing drug-induced and non-drug-induced changes. Studies reported an increased risk of QTc interval prolongations influenced by different therapies based on chloroquine, hydroxychloroquine, and azithromycin. Although these medications increased risks of severe QTc prolongations, they induced no arrhythmia-related deaths. In the non-drug-induced group, ST-T abnormalities, notably ST elevation, accounted for the most observed ECG finding in the patients with COVID-19, but their relation with myocardial injuries was under dispute. Conclusion: This systematic review suggests that identifying ECG patterns that might be related to COVID-19 is vital. Provided that physicians do not recognize these patterns, they might erroneously risk the lives of their patients. Furthermore, important drug-induced ECG changes provide awareness to the health-care workers on the risks of possible therapies.http://www.sciencedirect.com/science/article/pii/S001948322030273XElectrocardiographyCOVID-19SARS-CoV-2 |
spellingShingle | Esmaeil Mehraeen Seyed Ahmad Seyed Alinaghi Ali Nowroozi Omid Dadras Sanam Alilou Parnian Shobeiri Farzane Behnezhad Amirali Karimi A systematic review of ECG findings in patients with COVID-19 Indian Heart Journal Electrocardiography COVID-19 SARS-CoV-2 |
title | A systematic review of ECG findings in patients with COVID-19 |
title_full | A systematic review of ECG findings in patients with COVID-19 |
title_fullStr | A systematic review of ECG findings in patients with COVID-19 |
title_full_unstemmed | A systematic review of ECG findings in patients with COVID-19 |
title_short | A systematic review of ECG findings in patients with COVID-19 |
title_sort | systematic review of ecg findings in patients with covid 19 |
topic | Electrocardiography COVID-19 SARS-CoV-2 |
url | http://www.sciencedirect.com/science/article/pii/S001948322030273X |
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