Determination of the Structural Integrity and Stability of Polysialic Acid during Alkaline and Thermal Treatment

Determination of the Structural Integrity and Stability of Polysialic Acid during Alkaline and Thermal Treatment

Polysialic acid (polySia) is a linear homopolymer of varying chain lengths that exists mostly on the outer cell membrane surface of certain bacteria, such as <i>Escherichia coli</i> (<i>E. coli</i>) K1. PolySia, with an average degree of polymerization of 20 (polySia avDP20),...

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Bibliographic Details
Main Authors: Bastian Bartling, Johanna S. Rehfeld, Daniel Boßmann, Ingo de Vries, Jörg Fohrer, Frank Lammers, Thomas Scheper, Sascha Beutel
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Molecules
Subjects:
polysialic acid
endotoxin removal
structure integrity
hydrolysis
nmr spectroscopy
Online Access:https://www.mdpi.com/1420-3049/25/1/165

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