The Mycotoxin De-Epoxy-Deoxynivalenol (DOM-1) Increases Endoplasmic Reticulum Stress in Ovarian Theca Cells

The Mycotoxin De-Epoxy-Deoxynivalenol (DOM-1) Increases Endoplasmic Reticulum Stress in Ovarian Theca Cells

Deoxynivalenol (DON) is a major mycotoxin present in animal feed and negatively affects growth and reproduction in farm species, including pigs and cattle. The mechanism of DON action involves the ribotoxic stress response (RSR), and it acts directly on ovarian granulosa cells to increase cell death...

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Bibliographic Details
Main Authors:	Angelica D. Reyes-Perea, Hilda M. Guerrero-Netro, Europa Meza-Serrano, Anthony Estienne, Christopher A. Price
Format:	Article
Language:	English
Published:	MDPI AG 2023-03-01
Series:	Toxins
Subjects:	deoxynivalenol follicle cattle steroidogenesis autophagy
Online Access:	https://www.mdpi.com/2072-6651/15/3/228

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