Evaluation of chronic toxicity and carcinogenicity of ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate in Sprague–Dawley rats

Evaluation of chronic toxicity and carcinogenicity of ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate in Sprague–Dawley rats

Ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate, developed for use as a polymerization processing aid in the manufacture of fluoropolymers, was tested for its potential chronic toxicity and carcinogenicity in a 2-year oral dosing study in Sprague–Dawley rats. Male rats were given dail...

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Bibliographic Details
Main Authors: J.M. Caverly Rae, Lisa Craig, Theodore W. Slone, Steven R. Frame, L.William Buxton, Gerald L. Kennedy
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Toxicology Reports
Subjects:
Fluoropolymers
Chronic toxicity and carcinogenicity study
Sprague–Dawley rats
PPARα agonist
Online Access:http://www.sciencedirect.com/science/article/pii/S221475001530010X

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