Neoadjuvant systemic and intravesical chemotherapy with partial cystectomy for muscle invasive bladder cancer with concomitant CIS

The presence of carcinoma in situ (CIS) is traditionally a contraindication to bladder-sparing approaches for muscle invasive bladder cancer (MIBC). Strategies that might aid in bladder preservation for this population require further investigation. We report a case of MIBC with CIS treated with bot...

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Main Authors: Benjamin D. Plambeck, Tutku E. Tazegul, Ian M. McElree, Ryan L. Steinberg, Vignesh T. Packiam, Michael A. O'Donnell
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Urology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214442023002024
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author Benjamin D. Plambeck
Tutku E. Tazegul
Ian M. McElree
Ryan L. Steinberg
Vignesh T. Packiam
Michael A. O'Donnell
author_facet Benjamin D. Plambeck
Tutku E. Tazegul
Ian M. McElree
Ryan L. Steinberg
Vignesh T. Packiam
Michael A. O'Donnell
author_sort Benjamin D. Plambeck
collection DOAJ
description The presence of carcinoma in situ (CIS) is traditionally a contraindication to bladder-sparing approaches for muscle invasive bladder cancer (MIBC). Strategies that might aid in bladder preservation for this population require further investigation. We report a case of MIBC with CIS treated with both neoadjuvant systemic and intravesical chemotherapy prior to partial cystectomy.
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spelling doaj.art-9180241d453243fb861e86adb7a3f4192023-09-09T04:55:33ZengElsevierUrology Case Reports2214-44202023-09-0150102516Neoadjuvant systemic and intravesical chemotherapy with partial cystectomy for muscle invasive bladder cancer with concomitant CISBenjamin D. Plambeck0Tutku E. Tazegul1Ian M. McElree2Ryan L. Steinberg3Vignesh T. Packiam4Michael A. O'Donnell5Department of Urology, University of Iowa Hospitals and Clinics, Iowa City, IA, United StatesUniversity of Iowa Carver College of Medicine, Iowa City, IA, United StatesUniversity of Iowa Carver College of Medicine, Iowa City, IA, United StatesDepartment of Urology, University of Iowa Hospitals and Clinics, Iowa City, IA, United StatesDepartment of Urology, University of Iowa Hospitals and Clinics, Iowa City, IA, United StatesDepartment of Urology, University of Iowa Hospitals and Clinics, Iowa City, IA, United States; Corresponding author. Department of Urology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA, 52242, United States.The presence of carcinoma in situ (CIS) is traditionally a contraindication to bladder-sparing approaches for muscle invasive bladder cancer (MIBC). Strategies that might aid in bladder preservation for this population require further investigation. We report a case of MIBC with CIS treated with both neoadjuvant systemic and intravesical chemotherapy prior to partial cystectomy.http://www.sciencedirect.com/science/article/pii/S2214442023002024Muscle invasive bladder cancerCarcinoma in situPartial cystectomyGemcitabineDocetaxel
spellingShingle Benjamin D. Plambeck
Tutku E. Tazegul
Ian M. McElree
Ryan L. Steinberg
Vignesh T. Packiam
Michael A. O'Donnell
Neoadjuvant systemic and intravesical chemotherapy with partial cystectomy for muscle invasive bladder cancer with concomitant CIS
Urology Case Reports
Muscle invasive bladder cancer
Carcinoma in situ
Partial cystectomy
Gemcitabine
Docetaxel
title Neoadjuvant systemic and intravesical chemotherapy with partial cystectomy for muscle invasive bladder cancer with concomitant CIS
title_full Neoadjuvant systemic and intravesical chemotherapy with partial cystectomy for muscle invasive bladder cancer with concomitant CIS
title_fullStr Neoadjuvant systemic and intravesical chemotherapy with partial cystectomy for muscle invasive bladder cancer with concomitant CIS
title_full_unstemmed Neoadjuvant systemic and intravesical chemotherapy with partial cystectomy for muscle invasive bladder cancer with concomitant CIS
title_short Neoadjuvant systemic and intravesical chemotherapy with partial cystectomy for muscle invasive bladder cancer with concomitant CIS
title_sort neoadjuvant systemic and intravesical chemotherapy with partial cystectomy for muscle invasive bladder cancer with concomitant cis
topic Muscle invasive bladder cancer
Carcinoma in situ
Partial cystectomy
Gemcitabine
Docetaxel
url http://www.sciencedirect.com/science/article/pii/S2214442023002024
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