Do prescription rates of psychotropic drugs change over three years from nursing home admission?
Abstract Background In this longitudinal study, we describe how psychotropic drugs (PTDs) are prescribed in nursing home (NH) patients from admission and over a 3-year period, to understand which clinical and environmental factors are associated with PTD prescription. Methods We used data from the R...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-09-01
|
| Series: | BMC Geriatrics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12877-021-02437-x |
| _version_ | 1818365075108397056 |
|---|---|
| author | Enrico Callegari Jūratė Šaltytė Benth Geir Selbæk Cato Grønnerød Sverre Bergh |
| author_facet | Enrico Callegari Jūratė Šaltytė Benth Geir Selbæk Cato Grønnerød Sverre Bergh |
| author_sort | Enrico Callegari |
| collection | DOAJ |
| description | Abstract Background In this longitudinal study, we describe how psychotropic drugs (PTDs) are prescribed in nursing home (NH) patients from admission and over a 3-year period, to understand which clinical and environmental factors are associated with PTD prescription. Methods We used data from the Resource Use and Disease Course in Dementia – Nursing Home (REDIC-NH) study, examining physical and mental health, dementia, and PTD prescription during a 3-year period from admission to a NH. Data were collected every six months. At baseline, we included 696 participants from 47 Norwegian NHs. We presented prevalence, incidence, and deprescribing rates of PTD prescriptions for each assessment point. We calculated the odds of receiving PTDs and used a generalized linear mixed model to analyze the variables associated with a change in odds throughout the 3-year period. Results PTD prescriptions were frequent throughout the 3-year period. Antidepressants had the highest prescription rates (28.4%–42.2%). Every PTD category had the highest incidence rate between admission and six months, and antipsychotics had the highest values (49.4%). Deprescribing rates were comparable between assessment points. The odds of antipsychotic prescriptions were lower for older people (OR = 0.96, 95%CI:0.92–0.99, p = 0.023). People with more severe dementia had lower odds of being prescribed sedatives/hypnotics (OR = 0.89, 95%CI:0.85–0.94, p < 0.001). Conclusions PTDs, particularly antidepressants, are widely prescribed over time to NH patients. Older patients are less likely to receive antipsychotics. A higher severity of dementia decreases the odds of being prescribed sedatives/hypnotics. Close attention should be paid to PTD prescriptions during long-term NH stay to avoid prolonged and excessive treatment with these types of drugs. Trial registration ClinicalTrials.gov Identifier: NCT01920100 . |
| first_indexed | 2024-12-13T22:14:29Z |
| format | Article |
| id | doaj.art-91811efa5ace4db2bcfd4a3f00cf5e5e |
| institution | Directory Open Access Journal |
| issn | 1471-2318 |
| language | English |
| last_indexed | 2024-12-13T22:14:29Z |
| publishDate | 2021-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Geriatrics |
| spelling | doaj.art-91811efa5ace4db2bcfd4a3f00cf5e5e2022-12-21T23:29:38ZengBMCBMC Geriatrics1471-23182021-09-0121111510.1186/s12877-021-02437-xDo prescription rates of psychotropic drugs change over three years from nursing home admission?Enrico Callegari0Jūratė Šaltytė Benth1Geir Selbæk2Cato Grønnerød3Sverre Bergh4Østfold Hospital TrustInstitute of Clinical Medicine, Campus Ahus, University of OsloFaculty of Medicine, University of OsloØstfold Hospital TrustResearch Centre for Age-related Functional Decline and Diseases, Innlandet Hospital TrustAbstract Background In this longitudinal study, we describe how psychotropic drugs (PTDs) are prescribed in nursing home (NH) patients from admission and over a 3-year period, to understand which clinical and environmental factors are associated with PTD prescription. Methods We used data from the Resource Use and Disease Course in Dementia – Nursing Home (REDIC-NH) study, examining physical and mental health, dementia, and PTD prescription during a 3-year period from admission to a NH. Data were collected every six months. At baseline, we included 696 participants from 47 Norwegian NHs. We presented prevalence, incidence, and deprescribing rates of PTD prescriptions for each assessment point. We calculated the odds of receiving PTDs and used a generalized linear mixed model to analyze the variables associated with a change in odds throughout the 3-year period. Results PTD prescriptions were frequent throughout the 3-year period. Antidepressants had the highest prescription rates (28.4%–42.2%). Every PTD category had the highest incidence rate between admission and six months, and antipsychotics had the highest values (49.4%). Deprescribing rates were comparable between assessment points. The odds of antipsychotic prescriptions were lower for older people (OR = 0.96, 95%CI:0.92–0.99, p = 0.023). People with more severe dementia had lower odds of being prescribed sedatives/hypnotics (OR = 0.89, 95%CI:0.85–0.94, p < 0.001). Conclusions PTDs, particularly antidepressants, are widely prescribed over time to NH patients. Older patients are less likely to receive antipsychotics. A higher severity of dementia decreases the odds of being prescribed sedatives/hypnotics. Close attention should be paid to PTD prescriptions during long-term NH stay to avoid prolonged and excessive treatment with these types of drugs. Trial registration ClinicalTrials.gov Identifier: NCT01920100 .https://doi.org/10.1186/s12877-021-02437-xGeriatric pharmacotherapyPsychotropic drugsNursing homes |
| spellingShingle | Enrico Callegari Jūratė Šaltytė Benth Geir Selbæk Cato Grønnerød Sverre Bergh Do prescription rates of psychotropic drugs change over three years from nursing home admission? BMC Geriatrics Geriatric pharmacotherapy Psychotropic drugs Nursing homes |
| title | Do prescription rates of psychotropic drugs change over three years from nursing home admission? |
| title_full | Do prescription rates of psychotropic drugs change over three years from nursing home admission? |
| title_fullStr | Do prescription rates of psychotropic drugs change over three years from nursing home admission? |
| title_full_unstemmed | Do prescription rates of psychotropic drugs change over three years from nursing home admission? |
| title_short | Do prescription rates of psychotropic drugs change over three years from nursing home admission? |
| title_sort | do prescription rates of psychotropic drugs change over three years from nursing home admission |
| topic | Geriatric pharmacotherapy Psychotropic drugs Nursing homes |
| url | https://doi.org/10.1186/s12877-021-02437-x |
| work_keys_str_mv | AT enricocallegari doprescriptionratesofpsychotropicdrugschangeoverthreeyearsfromnursinghomeadmission AT juratesaltytebenth doprescriptionratesofpsychotropicdrugschangeoverthreeyearsfromnursinghomeadmission AT geirselbæk doprescriptionratesofpsychotropicdrugschangeoverthreeyearsfromnursinghomeadmission AT catogrønnerød doprescriptionratesofpsychotropicdrugschangeoverthreeyearsfromnursinghomeadmission AT sverrebergh doprescriptionratesofpsychotropicdrugschangeoverthreeyearsfromnursinghomeadmission |