Advancements in Layered Double Hydroxide-Based Chemotherapeutic Nanosystems for Cancer Treatment

Globally, Cancer therapy is still a major issue. With the latest developments in nanotechnology, layered double hydroxide (LDH)-based nanosystems are receiving special attention due to their pH dependent biodegradability, superior biocompatibility, easy surface modification, anion exchange capacity...

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Main Authors: S. I. Omonmhenle, I. H. Ifijen
Format: Article
Language:English
Published: Joint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP) 2023-04-01
Series:Journal of Applied Sciences and Environmental Management
Online Access:https://www.ajol.info/index.php/jasem/article/view/247050
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author S. I. Omonmhenle
I. H. Ifijen
author_facet S. I. Omonmhenle
I. H. Ifijen
author_sort S. I. Omonmhenle
collection DOAJ
description Globally, Cancer therapy is still a major issue. With the latest developments in nanotechnology, layered double hydroxide (LDH)-based nanosystems are receiving special attention due to their pH dependent biodegradability, superior biocompatibility, easy surface modification, anion exchange capacity and high chemical stability, giving rise to great potential for cancer therapy. By intercalating inorganic, organic, or bio molecules into their lamellar lattice, new hybrid materials with dual or multi-functional features, including anticancer capabilities, can be developed from layered double hydroxide (LDH). Despite the fact that outstanding research has been published, few review papers address these essential and promising discoveries to stimulate the ongoing development of LDH-based nanosystems in the field of cancer therapy. This paper therefore study focuses on the most recent advancements in LDH-based chemotherapeutic nanosystems for cancer treatment. The information utilized in this review was gathered from studies that have previously been published and were retrieved from several Journal outlets. These reports dealt with the usage of layered doubled hydroxide-based chemotherapeutic nanosystems for the treatment of cancer. The research demonstrates that layered double hydroxides may be utilized to develop single or composite nanosystems that distribute therapeutic components precisely without causing cumulative damage for the field of nanomedicine.
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spelling doaj.art-9181eace74ba45c39eabd8d2a6b30f242024-04-01T15:17:31ZengJoint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP)Journal of Applied Sciences and Environmental Management2659-15022659-14992023-04-0127410.4314/jasem.v27i4.24Advancements in Layered Double Hydroxide-Based Chemotherapeutic Nanosystems for Cancer TreatmentS. I. OmonmhenleI. H. Ifijen Globally, Cancer therapy is still a major issue. With the latest developments in nanotechnology, layered double hydroxide (LDH)-based nanosystems are receiving special attention due to their pH dependent biodegradability, superior biocompatibility, easy surface modification, anion exchange capacity and high chemical stability, giving rise to great potential for cancer therapy. By intercalating inorganic, organic, or bio molecules into their lamellar lattice, new hybrid materials with dual or multi-functional features, including anticancer capabilities, can be developed from layered double hydroxide (LDH). Despite the fact that outstanding research has been published, few review papers address these essential and promising discoveries to stimulate the ongoing development of LDH-based nanosystems in the field of cancer therapy. This paper therefore study focuses on the most recent advancements in LDH-based chemotherapeutic nanosystems for cancer treatment. The information utilized in this review was gathered from studies that have previously been published and were retrieved from several Journal outlets. These reports dealt with the usage of layered doubled hydroxide-based chemotherapeutic nanosystems for the treatment of cancer. The research demonstrates that layered double hydroxides may be utilized to develop single or composite nanosystems that distribute therapeutic components precisely without causing cumulative damage for the field of nanomedicine. https://www.ajol.info/index.php/jasem/article/view/247050
spellingShingle S. I. Omonmhenle
I. H. Ifijen
Advancements in Layered Double Hydroxide-Based Chemotherapeutic Nanosystems for Cancer Treatment
Journal of Applied Sciences and Environmental Management
title Advancements in Layered Double Hydroxide-Based Chemotherapeutic Nanosystems for Cancer Treatment
title_full Advancements in Layered Double Hydroxide-Based Chemotherapeutic Nanosystems for Cancer Treatment
title_fullStr Advancements in Layered Double Hydroxide-Based Chemotherapeutic Nanosystems for Cancer Treatment
title_full_unstemmed Advancements in Layered Double Hydroxide-Based Chemotherapeutic Nanosystems for Cancer Treatment
title_short Advancements in Layered Double Hydroxide-Based Chemotherapeutic Nanosystems for Cancer Treatment
title_sort advancements in layered double hydroxide based chemotherapeutic nanosystems for cancer treatment
url https://www.ajol.info/index.php/jasem/article/view/247050
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