PD-1/PD-L1 Checkpoint Inhibitors Are Active in the Chicken Embryo Model and Show Antitumor Efficacy <i>In Ovo</i>

PD-1/PD-L1 Checkpoint Inhibitors Are Active in the Chicken Embryo Model and Show Antitumor Efficacy <i>In Ovo</i>

(1) Purpose: To assess the use of the chicken embryo (<i>in ovo</i>) model as an alternative <i>in vivo</i> model for immuno-oncology (IO) drug development, focusing on programmed cell death protein-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) immune checkpoint inhibitors....

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Bibliographic Details
Main Authors: Yan Wang, Xavier Rousset, Chloé Prunier, Paul Garcia, Emilien Dosda, Estelle Leplus, Jean Viallet
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cancers
Subjects:
chicken embryo
<i>in ovo</i>
CAM assay
PD-1/PD-L1 inhibitor
immuno-oncology
Online Access:https://www.mdpi.com/2072-6694/14/13/3095

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