Interferon lambda in respiratory viral infection: immunomodulatory functions and antiviral effects in epithelium

Interferon lambda in respiratory viral infection: immunomodulatory functions and antiviral effects in epithelium

Type III interferon (IFN-λ), a new member of the IFN family, was initially considered to possess antiviral functions similar to those of type I interferon, both of which are induced via the JAK/STAT pathway. Nevertheless, recent findings demonstrated that IFN-λ exerts a nonredundant antiviral functi...

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Bibliographic Details
Main Authors: Yong-Guang Liu, Su-Wei Jin, Shan-Shan Zhang, Tian-Ji Xia, Yong-Hong Liao, Rui-Le Pan, Ming-Zhu Yan, Qi Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
interferon lambda
respiratory tract
viral infection
type III interferon
immunity
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1338096/full

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